维生素D在子宫内膜异位症中的作用研究进展

维生素D除了调节机体钙磷代谢维持骨骼强壮外，还具有免疫调节、抗炎等作用，与慢性炎症性疾病、免疫疾病、肿瘤等有关。近年研究发现，维生素D可通过调节免疫、炎症反应、细胞增殖及凋亡、血管生成、细胞黏附及侵袭等方面参与子宫内膜异位症的发病；补充维生素D可缓解子宫内膜异位症相关疼痛，改善内膜容受性，防治子宫内膜异位症。本文就近年来维生素D在子宫内膜异位症中的作用及机制研究进展作一综述。
Abstract: In addition to regulating calcium and phosphorus metabolism to maintain strong bones, vitamin D also has immune regulating and anti-inflammatory effects. Moreover, it is related to chronic inflammatory diseases, autoimmune diseases and cancer. Many studies indicate the roles of vitamin D in the development and progression of endometriosis including the effects on modulation of immune responses, inflammation reactions, cell proliferation and apoptosis, angiogenesis, adhesion and invasion. Vitamin D supplementation can relieve pain and improve endometrial receptivity associated with endometriosis and play a preventive and therapeutic role. This paper summarizes the roles of vitamin D in endometriosis. Key words: Endometriosis Vitamin D Immunocompetence Review