丙型肝炎病毒在辅助生殖技术中的存在与垂直传播

垂直传播是儿童感染丙型肝炎病毒(HCV)的主要方式,近年来受到广泛关注。随着辅助生殖技术的发展,越来越多的HCV感染不孕夫妇寻求辅助生殖技术治疗以获得后代。辅助生殖技术过程中HCV的垂直传播现象仍不可避免,了解HCV在母体和胚胎内的存在与风险,有利于在解决生育问题的同时更好地控制HCV的垂直传播,预防儿童感染。
Abstract: Vertical transmission is the major route of HCV infection in children and draws much attention recently. With the development of assisted reproductive technology (ART), more and more HCV-serodiscordant infertile couples seek assisted reproduction treatment. Vertical transmission of HCV in ART cannot be avoided. Understanding the state of HCV infection of oocyte and embryo is helpful to solve the fertility problem and to control mother-to-child transmission. Key words: Hepacivirus/immunology Hepatitis C/transmission Disease transmission, vertical Reproductive techniques, assisted Oocytes Fetal diseases Review