拉克替醇联合复方聚乙二醇在住院患者结肠镜检查前肠道准备中的应用

摘要： 目的??观察拉克替醇联合复方聚乙二醇用于住院患者结肠镜检查前肠道准备的临床效果。方法?选择205名拟行结肠镜检查的住院患者，随机分为实验组（拉克替醇联合复方聚乙二醇）102例和对照组（复方聚乙二醇）103例。观察两组肠道清洁效果及不良反应发生率。结果?实验组肠道清洁效果与对照组无明显差异，但实验组肠道清洁度为1级者明显高于对照组；实验组不良反应发生率更低，对夜间睡眠几无影响，明显提高了住院患者的依从性及耐受性。结论?拉克替醇联合复方聚乙二醇用于住院患者肠道准备安全、有效，不良反应少。
Abstract: Objective?To evaluate the efficacy of combined application of lactitol oral solution and polyethylene glycol electrolyte (PEG) powder compared with conventional method in bowel preparation before colonoscopy.?Methods?205 patients who underwent colonoscopy were randomly divided into experimental group and control group. The experimental group (n = 102) were given lactitol and polyethylene glycol electrolyte powder, whereas the patients in control group (n = 103) were given polyethylene glycol electrolyte powder only. The visibility and adverse effects during colonoscopy were observed.?Results?The cleaning satisfaction rate was not statistically significant between the two groups. The proportion of cleanliness to grade 1 in experimental group was higher than that in control group. The incidence of adverse effects in experimental group was lower, and there was no effect on sleeping night. The compliance and tolerance of hospitalized patients were significantly improved.?Conclusion?Lactitol combined with polyethylene glycol electrolyte (peg) powder is safe, effective, with low incidence of adverse effect for bowel preparation in hospitalized patients.