OTSC金属夹治疗难治性急性非静脉曲张性上消化道出血的效果评估

摘要： 目的??探讨内镜下OTSC金属夹闭合术在难治性急性非静脉曲张性上消化道出血（ANVUGIB）治疗中的疗效。方法?对滨州医学院附属医院消化内科2015年1月1日-2016年6月1日通过OTSC金属夹治疗的16例难治性ANVUGIB的患者进行回顾性分析。其中贲门黏膜撕裂并出血2例，胃溃疡出血7例，胃癌1例，十二指肠球部溃疡出血6例。结果?16例患者均成功的进行了内镜下止血，成功率100.0%，止血夹自安装至释放成功平均所需时间仅为5.0～6.0 min。结论?OTSC在难治性ANVUGIB患者中的治疗安全、有效，值得临床推广。
Abstract: Objective?To evaluate the clinical efficacy of the over-the-scope-clip (OTSC) for endoscopic closure of acute refractory non-variceal upper gastrointestinal bleeding.?Methods?This retrospective study selected 16 refractory patients, including 2 cases with Mallory-Weiss syndrome, 7 cases with gastric ulcer, 1 case with gastric carcinoma and 6 cases with duodenal ulcer, underwent OTSC treatment of acute non-variceal upper gastrointestinal bleeding from January 2015 to June 2016 as study subjects.?Results?All of the 16 patients with bleeding lesions were successfully controlled. The successful rate is 100.0%. The mean procedure of OTSC for endoscopic bleeding closure was between 5.0 and 6.0 min.?Conclusion?The Over-the-Scope-Clip system is safe and effective for closure of acute non-variceal upper gastrointestinal bleeding in refractory patients, and deserves further clinical applications.