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- 2017
比较 2 种微导丝对脑卒中支架取栓速度及安全性的影响
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Abstract:
目的 · 比较0.014 in 的 Synchro 微导丝和Transend 微导丝对急性缺血性脑卒中支架取栓的速度及安全性的影响。方法 · 入 组 2012 年 10 月至2017 年 1 月在上海交通大学医学院附属第九人民医院接受机械取栓的急性缺血性卒中患者46 例，分为Synchro 组（21 例）和Transend 组（25 例），比较2 组手术操作时间及安全性等指标。结果· 2 组闭塞血管再通率类似（P=0.600），但 Synchro 组从股动脉穿刺至血管再通时间显著短于 Transend 组（48.88 min vs 82.33 min，P=0.001)。2 组患者术后 3 个月获得功能独立 （mRS ≤ 2）的比例类似（P=1.000），操作后蛛网膜下腔出血发生率类似（P=1.000）。但 Transend 组有2 例因血管穿孔导致严重蛛网 膜下腔出血伴血肿，均死亡；Synchro 组仅有 1 例轻微的单纯蛛网膜下腔出血，恢复良好。结论 · 和 Transend 微导丝相比，Synchro 微 导丝能够缩短支架取栓操作时间，致命性蛛网膜下腔出血风险较小。
： Objective · To compare the impacts on clinical efficiency and safety between 0.014 inch Synchro microwire and Transend microwire used during mechanical thrombectomy for acute ischemic stroke (AIS) caused by large artery occlusion. Methods · Forty-six patients undergoing mechanical thrombectomy with stent retrievers between October 2012 and January 2016 were included, who were classified into Synchro group (21 cases) and Transend group (25 cases). The clinical outcome, procedure time, and safety were analyzed and compared between two groups. Results · The recanalization rates were similar between two groups (P=0.600) , but time from puncture to vascular recanalization of Synchro group was much shorter than that of Transend goup (48.88 min vs 82.33 min, P=0.001). The rates of functional independence (modified Rankin scale score ≤ 2) were similar between two groups (P=1.000). There was no significant difference of the rates of post-procedure subarachnoid hemorrhage (PSAH) between two groups (P=1.000). However, there were two cases that had fatal subarachnoid hemorrhage with intracranial hematoma in Transend group, while there was only one case of mild subarachnoid hemorrhage who recovered well in Synchro group. Conclusion · Compared with Transend microwire, Synchro microwire can significantly shorten the procedure time of mechanical thrombectomy, and the risk of fatal subarachnoid hemorrhage is rather small
