儿童难治性支原体肺炎诊治进展
Progresses of diagnosis and treatment of children with refractory mycoplasma pneumoniae

肺炎支原体（MP）是引起儿童呼吸道感染的常见病原菌。MP感染通常是一个自限性、良性过程，大多经大环内酯类治疗有效。但近年来发现，部分患儿虽经正规大环内酯类抗生素治疗1周或1周以上，其临床症状和影像学表现仍无明显改善，病情加重或迁延不愈，甚至出现一些严重的后遗症，导致难治性支原体肺炎（RMPP）的发生。RMPP病例呈逐年增多趋势，在早期诊断和治疗上存在很多困难。该文就RMPP诊断和治疗进展作一综述。
： Mycoplasma pneumoniae (MP) is a common pathogen that can cause communityacquired pneumonia of children. The infection of MP is usually a benign and self-limited process and can be effectively treated with macrolides. But in recent years, it was discovered that clinical symptoms and imaging findings of some cases did not improve after being regularly treated with macrolide antibiotics for more than 1 week. Their conditions were worse or protracted. Even some serious sequelae developed and resulted in refractory mycoplcasma pneumoniae pneumonia (RMPP). Cases of RMPP increase year by year and there are many difficulties for early diagnosis and treatment. This paper reviews progresses of the diagnosis and treatment of RMPP