眼球运动在帕金森病中的研究进展
Research progresses of eye movement in Parkinsons disease

帕金森病是一种症状多样、机制复杂的神经退行性疾病。近年来，随着对帕金森病致病机制、生物标志物等研究的深入，越来越多的研究者发现眼球运动的异常在帕金森病中有着重要的意义。该文主要总结了近10余年来国内外学者对于眼球运动异常和帕金森病的相关研究，并对其病理生理机制、临床研究的设计和作为生物标志物对帕金森病的诊断与鉴别的价值进行了初步的探讨。
： Parkinsons disease is a multifaceted neurodegenerative disorder with complicated mechanism and various symptoms. In recent years, with the deepening of the research on the pathogenesis and biomarkers of Parkinsons disease, a growing number of researchers have found that eye movement abnormalities play an important role in Parkinsons disease. This paper mainly summarizes the latest research progresses of eye movement disorders and Parkinsons disease, and explores pathophysiological mechanism, design of clinical research, and the value of eye movement as a biomarker in diagnosis and differentiation of Parkinson’s disease