Cleft palate or harelip is one of the most common congenital defects in humans and harelip with cleft lip in whites is estimated 1 out of every 7000 to 1000 births. In recent years, surgeons and doctors have tried to resolve this problem immediately after the birth by operation, but sometimes we encounter things that cannot be easily solved by a surgical procedure. Our goal is to use stem cells to eliminate the disease and prevent operation, because children are often afraid of surgery and pain later on. Also, the need for general anesthesia for bone remodeling involves complications, such as long-term pain and nerve disorders. By the advent of the use of alternative stem extraction techniques, a better alternative to the invasive method of cleft lip and palate therapy has been developed.
References
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Bueno, D.F. (2008) New Source of Muscle-Derived Stem Cells with Potential for Alveolar Bone Reconstruction in Cleft Lip and/or Palate Patients. University of São Paulo, São Paulo, 54-58.
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Sadegi, S. and Zaban, A.K. (2014) Seperation, Cultivation and Identification of Mezanchimic Stem Cells Driven of Fat Tissue of Human Being. Tehran Medical Faculty Magazine, 27-32.
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Alviano, F., Fossati, V., Marchionni, C., Arpinati, M., Bonsi, L., Franchina, M., et al. Term Amniotic Membrane Is a High Throughput Source for Multipotentmesenchymal.
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Portmann-Lanz, C.B., Schoeberlein, A. and Huber, A. (2006) Placental Mesenchymal Stem Cells as Potential Autologous Graft for Pre- and Perinatal Neurodegeneration. American Journal of Obstetrics and Gynecology, 194, 664-673. https://doi.org/10.1016/j.ajog.2006.01.101
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Karahuseyinoglu, S., Cinar, O., Kilic, E., Kara, F., Akay, G.G., Demiralp, D.O., et al. (2007) Biology of Stem Cells in Human Umbilical Cord Stroma: In Situ and In Vitro Surveys. Stem Cells, 25, 319-331. https://doi.org/10.1634/stemcells.2006-0286
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Abdollahi, Z. and Mirzapoor, T. (2010) The Investigation of Stemming Cells of Mezanchimic Jelly Warton of Umbilical Cord during Distinction to Same Cells. New Cell and Mol Biotechnology Magazine, 54-58.
