Introduction: Abnormal uterine bleeding, either due to organic or be dysfunctional
cause, is a common gynaecological problems. Methods:A retrospective,
cross sectional, hospital-based study was done for a period of five and a half
years included 1884 samples which were taken by endosampling as well as by
curetting for the evaluation of several gynaecological symptoms.Results:The age distribution ranges from16 to 83 years. 12.8% of (242/1884) samples
were inadequate for a comprehensive diagnosis. The functional cause was the
predominant in 1263 samples and organic causes were found in 379 sample. Themenorrhagia is the commonest one and it is followed by post-menopausal
bleeding and polymenorrhoea. Endometrial polyp was the predominant organic (46.9%)
cause followed by (26.1%) simple endometrial hyperplasia without atypia. Most
of the simple hyperplasia without atypia (49/99) and complex hyperplasia
(10/28) also occurred in the same age group. Total 29 (1.5%) cases of carcinoma
of endometrium were found and it was common (13/29) in 50-59
years of age. It was noted that (5/29) carcinoma occurred in less than 39 years
of age.
References
[1]
Tavassoli, F.A. and Devilee, P., Eds. (2003) Tumors of the Uterine Corpus. In: WHO Classifications of Tumours. Pathology and Genetics of Tumors of the Breast and Female Genital Organs, IARC Press, Lyon, 221-232.
[2]
Kumar, P. and Malhotra, N. (2008) Jeffcoate’s Principles of Gynaecology. 7th Edition, JBMP, India, 598-616.
[3]
Shwayder, J.M. (2000) Pathophysiology of Abnormal Uterine Bleeding. Obstetrics and Gynecology Clinics of North America, 27, 219-234.
https://doi.org/10.1016/S0889-8545(00)80017-0
[4]
Parveen, F. and Hashim, H.A. (1999) Dysfunctional Uterine Bleeding: A Histopathology Study. Journal of the College of Physicians and Surgeons Pakistan, 9, 318-320.
Telner, D.E. and Jakubovicz, D. (2007) Approach to Diagnosis and Management of Abnormal Uterine Bleeding. Canadian Family Physician, 53, 58-64.
[7]
Clark, T.J. and Gupta, J.K. (2002) Endometrial Sampling of Gynaecological Pathology. The Obstetrician and Gynaecologist, 4, 169-174.
https://doi.org/10.1576/toag.2002.4.3.169
[8]
Vigod, S.N. and Stewart, D.E. (2002) Management of Abnormal Uterine Bleeding by Northern, Rural and Isolated Primary Care Physicians: PART I—How Are We Doing? BMC Women Health, 2, 10. https://doi.org/10.1186/1472-6874-2-10
[9]
Brand, A., Duduc-Lissoir, J., Ehlen, T.G. and Plante, M. (2000) Diagnosis of Endometrial Cancer in Women with Abnormal Vaginal bleeding. SOGC Clinical Practice Guidelines, 22, 102-104.
[10]
Fakhar, S., Saeed, G., Khan, A.H. and Alam, A.Y. (2008) Validity of Pipelle Endometrial Sampling in Patients with Abnormal Uterine Bleeding. Annals of Saudi Medicine, 28, 188-191. https://doi.org/10.4103/0256-4947.51721
[11]
Bhosle, A. and Fonseca, M. (2010) Evaluation and Histopathological Correlation of Abnormal Uterine Bleeding in Perimenopausal Women. Bombay Hospital Journal, 52, 69-72.
[12]
Mahapatra, M. and Mishra, P. (2015) Clinicopathological Evaluation of Abnormal Uterine Bleeding. Journal of Health Research and Reviews, 2, 45-49.
https://doi.org/10.4103/2394-2010.160904
[13]
Kaul, I., Kalsi, M., Anand, A.K., Jad, R. and Menia, V. (2012) Transvaginal Sonography versus Histopathology in Postmenopausal Bleeding: A Prospective Study. JK Science, 14, 129-133.
[14]
Bharti, B. and Satish, R.P. (2008) Feasibility, and Yield of Endometrial Biopsy Using Suction Curette Device for Evaluation of Abnormal Pre and Postmenopausal Bleeding. The Journal of Obstetrics and Gynecology of India, 58, 322-326.
[15]
Khan, R., Sherwani, R., Rana, S., Hakim, S. and Jairajpuri, Z. (2016) Clinco-Pathological Patterns in Women with Dysfunctional Uterine Bleeding. Iranian Journal of Pathology, 11, 20-26.
[16]
Baral, R. and Pudasini, S. (2011) Histopathological Pattern of Endometrial Samples in Abnormal Uterine Bleeding. Journal of Pathology of Nepal, 1, 13-16.
[17]
Muzzafar, M., Akhtar, K.A.K., Yasmin, S., Rehman, M., Iqbal, W. and Khan, M.A. (2005) Menstrual Irregularities with Excessive Blood Loss: A Clinico-Pathological Correlation. Journal of Pakistan Medical Association, 55, 486-489.
[18]
Silander, T. (1962) Hysteroscopy through a Transparent Rubber Balloon. Surgery, Gynecology & Obstetrics, 114, 125.
[19]
Abdullah, L.S. and Bondagji, N.S. (2011) Histopathological Pattern of Endometrial Sampling Performed for Abnormal Uterine Bleeding. Bahrain Medical Bulletin, 33, 1-6.
[20]
Dexous, S., Labastida, R. and Arias, A. (1984) Hysteroscopy in Abnormal Uterine Bleeding. In: Segler, A.M., Ed., Linde Hysteroscopy: Principles and Practice, JB Lipponcott, Philadelphia, 121-134.
[21]
Reed, S.D., Newton, K.M., Clinton, W.L., Epplein, M., Garacia, R., Allison, K., et al. (2009) Incidence of Endometrial Hyperplasia. American Journal of Obstetrics & Gynecology, 200, 678.e1-678.e6. https://doi.org/10.1016/j.ajog.2009.02.032