Polymer gels are three-dimensional dosimetric tools. The purpose of the present study was to investigate the temperature dependence of polymer gels during scanning Magnetic Resonance Imaging. Prepared gels were irradiated with a 6MV X-ray beam at intensities ranging from 0 to 20 Gy in order to investigate their dose-R2 and dose-R1 responses. Irradiated gels were evaluated from 1.5-T magnetic resonance R2 and R1 images for each 5°C change in temperature from 5°C to 41°C, and then the four-field box technique irradiation plan was used to deliver a total dose of 4 Gy using the same beam weight in each direction to the prepared gels. The profile of the dose map generated from the four-field irradiated gel data at 20°C was then compared with the planned data. The dose-R2 response curve was linear up to 20 Gy at 20°C, with a slope of 1.17 Gy-1˙s-1. The slopes of the fitted curves of the dose-R2 decreased as gel temperature increased. The slopes of the dose-R1 curves were more parallel than the slopes of the dose-R2 curves between 5 and 41°C. The difference in the full width of half maximum of the gel profile data obtained using the four-field box technique at 20°C and the planned data were below 5% on average. The dose map from the irradiated gels obtained using the dose-R2 curve was the same as that from the planned data under the same temperature conditions. Measurement of difference between various temperatures is significant with dose accuracy. It is suitable to evaluate the gel dosimeter under the thermal equilibrium condition, MRI room temperature from the point of view of the stability of the irradiated gels.
References
[1]
Baldock, C., De Deene, Y., Doran, S., Ibbott, G., Jirasek, A., Lepage, M., McAuley, KB., Oldham, M. and Schreiner, L.J. (2010) Polymer Gel Dosimetry. Physics in Medicine & Biology, 55, R1-R63. https://doi.org/10.1088/0031-9155/55/5/R01
[2]
Kawamura, H., Sakae, T., Terunuma, T., Ishida, M., Shibata, Y. and Matsumura, A. (2013) Evaluation of Three-Dimensional Polymer Gel Dosimetry Using X-Ray CT and R2 MRI. Applied Radiation and Isotopes, 77, 94-102. https://doi.org/10.1016/j.apradiso.2013.02.011
[3]
Ceberg, S., Gagne, I., Gustafsson, H., Scherman, J.B., Korreman, S.S., Kjaer-Kristoffersen, F., Hilts, M. and Bäck, S.A. (2010) Rapid Arc Treatment Verification in 3D Using Polymer Gel Dosimetry and Monte Carlo Simulation. Physics in Medicine & Biology, 55, 4885-4898. https://doi.org/10.1088/0031-9155/55/17/001
[4]
Novotny, J., Dvorák, P., Spevácek, V., Tintera, J., Novotny, J., Cechák, T. and Liscák, R. (2002) Quality Control of the Stereotactic Radiosurgery Procedure with the Polymer-Gel Dosimetry. Radiotherapy and Oncology, 63, 223-230. https://doi.org/10.1016/S0167-8140(02)00064-6
[5]
Hayashi, N., Malmin, R.L. and Watanabe, Y. (2014) Dosimetric Verification for Intensity-Modulated Arc Therapy Plans by Use of 2D Diode Array, Radiochromic Film and Radiosensitive Polymer Gel. Journal of Radiation Research, 55, 541-552. https://doi.org/10.1093/jrr/rrt139
[6]
De Deene, Y., De Wagter, C., Van Duyse, B., Derycke, S., De Neve, W. and Achten, E. (1998) Three-Dimensional Dosimetry Using Polymer Gel and Magnetic Resonance Imaging Applied to the Verification of Conformal Radiation Therapy in Head-and-Neck Cancer. Radiotherapy and Oncology, 48, 283-291. https://doi.org/10.1016/S0167-8140(98)00087-5
[7]
De Deene, Y., Vergote, K., Claeys, C. and De Wagter, C. (2006) The Fundamental Radiation Properties of Normoxic Polymer Gel Dosimeters: A Comparison between a Methacrylic Acid Based Gel and Acrylamide Based Gels. Physics in Medicine & Biology, 51, 653-673. https://doi.org/10.1088/0031-9155/51/3/012
[8]
Maryanski, M.J., Audet, C. and Gore, J.C. (1997) Effects of Crosslinking and Temperature on the Dose Response of a BANG Polymer Gel Dosimeter. Physics in Medicine & Biology, 42, 303-311. https://doi.org/10.1088/0031-9155/42/2/004
[9]
Scheib, S.G., Schenkel, Y. and Gianolini, S. (2004) Absolute Dose Verifications in Small Photon Fields Using BANGTM Gel. Journal of Physics: Conference Series, 3, 228-231. https://doi.org/10.1088/1742-6596/3/1/034
[10]
Spevacek, V., Novotny, J.Jr., Dvorak, P., Novotny, Jr., Vymazal, J. and Cechak. T. (2001) Temperature Dependence of Polymer-Gel Dosimeter Nuclear Magnetic Resonance Response. Medical Physics, 28, 2370-2378. https://doi.org/10.1118/1.1410124
[11]
Hrbacek, J., Spevacek, V., Novotny, Jr. and Cechak, T. (2004) A Comparative Study of Four Polymer Gel Dosimeters. Journal of Physics: Conference Series, 3, 150-154. https://doi.org/10.1088/1742-6596/3/1/015
[12]
Fuse, H., Shinoda, K., Inohira, M., Kawamura, H., Miyamoto, K., Sakae, T. and Fujisaki T. (2015) Utilization of Polymer Gel as a Bolus Compensator and a Dosimeter in the Near-Surface Buildup Region for Breast-Conserving Therapy. Review of Scientific Instruments, 86, Article ID: 096103. https://doi.org/10.1063/1.4930554
[13]
Kawamura, H., Shinoda, K., Fuse, H., Terunuma, T., Miyamoto, K., Sakae, T. and Matsumura, A. (2013) Comparison between Polymer Gel Dosimetry and Calculated Dose with Small Field in Stereotactic Irradiation. Journal of Physics: Conference Series, 444, Article ID: 012031. https://doi.org/10.1088/1742-6596/444/1/012031
[14]
Vandecasteele, J. and De Deene, Y. (2013) On the Validity of 3D Polymer Gel Dosimetry: III. MRI-Related Error Sources. Physics in Medicine & Biology, 58, 63-85. https://doi.org/10.1088/0031-9155/58/1/63
[15]
Murakami, Y., Nakashima, T., Watanabe, Y., Akimitsu, T., Matsuura, K., Kenjo, M., et al. (2007) Evaluation of the Basic Properties of the BANGkit Gel Dosimeter. Physics in Medicine & Biology, 52, 2301-2311. https://doi.org/10.1088/0031-9155/52/8/017
[16]
Mamisch, T.C., Trattnig, S., Quirbach, S., Marlovits, S., White, L.M. and Welsch, G.H. (2010) Quantitative T2 Mapping of Knee Cartilage: Differentiation of Healthy Control Cartilage and Cartilage Repair Tissue in the Knee with Unloading-Initial Results. Radiology, 254, 818-826. https://doi.org/10.1148/radiol.09090335
[17]
Nelson, T.R. and Tung, S.M. (1987) Temperature Dependence of Proton Relaxation Times in Vitro. Magnetic Resonance Imaging, 5, 189-199. https://doi.org/10.1016/0730-725X(87)90020-8
[18]
Bloembergen, N., Purcell, E.M. and Pound, R.V. (1948) Relaxation Effects in Nuclear Magnetic Resonance Absorption. Physical Review, 73, 679-721. https://doi.org/10.1103/PhysRev.73.679
[19]
Gore, J.C., Kang, Y.S. and Schulz, R.J. (1984) Measurement of Radiation Dose Distributions by Nuclear Magnetic Resonance (NMR) Imaging. Physics in Medicine & Biology, 29, 1189-1197. https://doi.org/10.1088/0031-9155/29/10/002
[20]
De Deene, Y. and De Wagter, C. (2001) Artefacts in Multi-Echo T2 Imaging for High-Precision Gel Dosimetry: III. Effects of Temperature Drift during Scanning. Physics in Medicine & Biology, 46, 2697-2711. https://doi.org/10.1088/0031-9155/46/10/312