Influence of distinct
radiotherapy techniques to induce second cancer risks in left breast cancer. Material
and methods: Ten female patients with intact left breast cancer. Two treatment plans for
each patient:1) two tangential beams
3D-Conformal radiotherapy, 2) intensity-modulated radiotherapy (IMRT) plan. Estimation of second cancer risk
from Organ equivalent dose models (OEDs) in three dose-response model for
organs at risk in left breast cases. Results: The P-value for OED models in
3D-IMRT for left lung, both lung, heart, right lung, right breast, thyroid,
liver and spinal cord in linear dose model was 0.016, 0.005, 0.019, 3.95E-06, 5.79E-07, 0.003, 1.78E
References
[1]
DeSantis, C., Ma, J., Bryan, L., et al. (2014) Breast Cancer Statistics. CA: A Cancer Journal for Clinicians, 64, 52-62. https://doi.org/10.3322/caac.21203
[2]
Freedman, A.N., Yu, B., Gail, M.H., et al. (2011) Benefit/Risk Assessment for Breast Cancer Chemoprevention with Raloxifene or Tamoxifen for Women Age 50 Years or Older. Journal of Clinical Oncology, 29, 2327-2333. https://doi.org/10.1200/JCO.2010.33.0258
[3]
Cordeiro, P.G. (2008) Breast Reconstruction after Surgery for Breast Cancer. The New England Journal of Medicine, 359, 1590-1601. https://doi.org/10.1056/NEJMct0802899
[4]
Zhang, P., Li, C.Z., Wu, C.T., Jiao, G.M., Yan, F., Zhu, H.C. and Zhang, X.-P. (2017) Comparison of Immediate Breast Reconstruction after Mastectomy and Mastectomy Alone for Breast Cancer: A Meta-Analysis. European Journal of Surgical Oncology, 43, 285-293. https://doi.org/10.1016/j.ejso.2016.07.006
[5]
Cahan, W.G., Woodard, H.Q., Higinbotham, L., Stewart, F.W. and Coley, B.L. (1948) Sarcoma Arising in Irradiated Bone: Report of Eleven Cases. Cancer, 1, 3-29. https://doi.org/10.1002/1097-0142(194805)1:1<3::AID-CNCR2820010103>3.0.CO;2-7
[6]
Suit, H., Goldberg, S., Niemierko, A., et al. (2007) Secondary Carcinogenesis in Patients Treated with Radiation: A Review on radiation-Induced Cancers in Human, Non-Human Primate, Canine and Rodent Subjects. Radiation Research, 167, 12-42. https://doi.org/10.1667/RR0527.1
[7]
Xu, X.G., Bernarz, B. and Paganetti, H. (2008) A Review of Dosimetry Studies on External-Beam Radiation Treatment with Respect to Second Cancer Induction. Physics in Medicine & Biology, 53, R193-R241. https://doi.org/10.1088/0031-9155/53/13/R01
[8]
Tubiana, M. (2009) Can We Reduce the Incidence of Second Primary Malignancies Occurring after Radiotherapy: A Critical Review. Radiotherapy & Oncology, 91, 4-15. https://doi.org/10.1016/j.radonc.2008.12.016
[9]
Shilkrut, M., Belkacemi, Y. and Kuten, A. (2012) Secondary Malignancies in Survivors of Breast Cancer: How to Overcome the Risk. Critical Reviews in Oncology/Hematology, 84, 86-89. https://doi.org/10.1016/j.critrevonc.2010.06.007
[10]
Woo, T.C., Pignol, J.P., Rakovitch, E., et al. (2006) Body Radiation Exposure in Breast Cancer Radiotherapy: Impact of Breast IMRT and Virtual Wedge Compensation Techniques. International Journal of Radiation Oncology, Biology, Physics, 65, 52-58. https://doi.org/10.1016/j.ijrobp.2005.11.023
[11]
Sachs, R.K., Brener, D.J., et al. (2005) Solid Tumor Risks after High Doses of Ionizing Radiation. Proceedings of the National Academy of Sciences of the United States of America, 102, 13040-13045. https://doi.org/10.1073/pnas.0506648102
[12]
Sakthivela, V., Mania, G., Mani, S. and Boopathy, R. (2017) Comparison of Treatment Planning Techniques in Treatment of Carcinoma of Left Breast: Second Cancer Perspective. Radiation Physics and Chemistry, 132, 41-45. https://doi.org/10.1016/j.radphyschem.2016.11.009
[13]
Schneider, U., Zwahlen, D., Ross, D., et al. (2005) Estimation of Radiation Induced Cancer from Three Dimensional Dose Distributions: Concept of Organ Equivalent Dose. International Journal of Radiation Oncology, Biology, Physics, 61, 1510-1515. https://doi.org/10.1016/j.ijrobp.2004.12.040
[14]
Rudat, V., Alaradi, A., Mohamed, A., AI-Yahya, K. and Altuwaijri, S. (2011) Tangential Beam IMRT versus Tangential Beam 3D-CRT of the Chest Wall in Post Mastectomy Breast Cancer Patients: A Dosimetric Comparison. Radiotherapy & Oncology, 6, 26. https://doi.org/10.1186/1748-717X-6-26
[15]
Schneider, U., Walsh, L., et al. (2008) Cancer Risk Estimates from the Combined Japanese A-Bomb and Hodgkins Cohorts for Doses Relevant to Radiotherapy. Radiation and Environmental Biophysics, 47, 253-263. https://doi.org/10.1007/s00411-007-0151-y
[16]
Kim, D., Chung, W., Shin, D., Hong, Park, S.H., Park, S.Y., Chung, K., Lim, Y.K., Shin, D., Lee, S.B., Lee, H.H. and Yoon, M. (2013) Risk of Second Cancer from Scattered Radiation of Intensity-Modulated Radiotherapies with Lung Cancer. Radiation Oncology, 8, 47. https://doi.org/10.1186/1748-717X-8-47
[17]
Zablotska, L.B. and Neugut, A.I. (2003) Lung Carcinoma after Radiation Therapy in Women Treated with Lumpectomy or Mastectomy for Primary Breast Carcinoma. Cancer, 97, 1404-1411. https://doi.org/10.1002/cncr.11214
[18]
Prochazka, M., Granath, F., Ekbom, A., Shields, P.G. and Hall, P. (2002) Lung Cancer risks in Women with Previous Breast Cancer. European Journal of Cancer, 38, 1520-1525. https://doi.org/10.1016/S0959-8049(02)00089-8
[19]
Galper, S., Gelman, R., Recht, A., Silver, B., Kohli, A., Wong, J.S., Van Buren, T., Baldini, E.H. and Harris, J.R. (2002) Second Nonbreast Malignancies after Conservative Surgery and Radiation Therapy for Early-Stage Breast Cancer. International Journal of Radiation Oncology, Biology, Physics, 52, 406-414. https://doi.org/10.1016/S0360-3016(01)02661-X
[20]
Fisher, B., Anderson, S., Bryant, J., Margolese, R.G., Deutsch, M., Fisher, E.R., Jeong, J.H. and Wolmark, N. (2002) Twenty-Year Follow-Up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer. The New England Journal of Medicine, 347, 1233-1241. https://doi.org/10.1056/NEJMoa022152
[21]
Roychoudhuri, R., Evans, H., Robinson, D. and Moller, H. (2004) Radiation-Induced Malignancies Following Radiotherapy for Breast Cancer. British Journal of Cancer, 91, 868-872. https://doi.org/10.1038/sj.bjc.6602084
[22]
van Dongen, J.A., Voogd, A.C., Fentiman, I.S., Legrand, C., Sylvester, R.J., Tong, D., van der Schueren, E., Helle, P.A., van Zijl, K. and Bartelink, H. (2000) Long-Term Results of a Randomized Trial Comparing Breast-Conserving Therapy with Mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial. Journal of the National Cancer Institute, 92, 1143-1150. https://doi.org/10.1093/jnci/92.14.1143
[23]
Blichert-Toft, M., Nielsen, M., During, M., Moller, S., Rank, F., Overgaard, M. and Mouridsen, H.T. (2008) Long-Term Results of Breast Conserving Surgery vs. Mastectomy for Early Stage Invasive Breast Cancer: 20-Year Follow-Up of the Danish Randomized DBCG-82TM Protocol. Acta Oncologica, 47, 672-681.
[24]
Hall, E.J. and Wuu, C.S. (2003) Radiation-Induced Second Cancers: The Impact of 3D-CRT and IMRT. International Journal of Radiation Oncology, Biology, Physics, 56, 83-88. https://doi.org/10.1016/S0360-3016(03)00073-7
[25]
Chaturvedi, A.K., Ahamad, A.A., Iyer, R.B., et al. (2007) Feasibility of Dose Escalation Using Intensity Modulated Radiotherapy in Posthysterectomy Cervical Carcinoma. Journal of the National Cancer Institute, 99, 1634-1643. https://doi.org/10.1093/jnci/djm201
[26]
Boice, J.D., Day, N.E., Anderson, A., et al. (1985) Second Cancers Following Radiation Treatment for Cervical Cancer. Journal of the National Cancer Institute, 74, 955-959.