A case of a 12-month-old male infant, who presented a painless swelling of the right anterolateral edge of the mobile tongue, is reported. The treatment consisted of a partial glossectomy with total surgical excision of the tumor. The diagnosis of low grade myofibroblastic sarcoma on the histological arguments (tumor architecture, cytology, mitotic index) and immunohistochemistry was retained.
References
[1]
Fletcher, C.D., Bridge, J., Hogendoorn, P. and Mertens, F. (2013) WHO Classification of Tumours of Soft Tissue and Bone. 4th Edition, IARC Press, Lyon, 15-18.
[2]
Vickie, Y., Jo, C. and Fletcher, D.M. (2014) WHO Classification of Soft Tissue Tumours: An Update Based on the 2013 (4th) Edition. Pathology, 46, 95-104.
https://doi.org/10.1097/PAT.0000000000000050
Mentzel, T., Dry, S., Katenkamp, D. and Fletcher, C.D. (1998) Low-Grade Myofibroblastic Sarcoma: Analysis of 18 Cases in the Spectrum of Myofibroblastic Tumors. American Journal of Surgical Pathology, 22, 1228-1238.
https://doi.org/10.1097/00000478-199810000-00008
[5]
Montgomery, E., Goldblum, J.R. and Fisher, C. (2001) Myofibroblastic Sarcoma: A Clinicopathologic Study. American Journal of Surgical Pathology, 28, 219-228.
https://doi.org/10.1097/00000478-200102000-00010
[6]
Alno, N., de Mello, G., Clipet, F., Roudi, P., Lombardi, T. and Samson, J. (2008) Sarcome myofibroblastique de bas grade: Encore un cas sur la langue. Médecine Buccale Chirurgie Buccale, 14, 239-244. https://doi.org/10.1051/mbcb/2008006
[7]
Neuville, A., Chibon, F. and Coindre, J.M. (2014) Grading of Soft Tissue Sarcomas: From Histological to Molecular Assessment. Pathology, 46, 113-120.
https://doi.org/10.1097/PAT.0000000000000048
[8]
Takácsi-Nagy, Z., Murakozy, G., Pogány, P., Fodor, J. and Orosz, Z. (2009) Myofibroblastic Sarcoma of the Base of Tongue. Case Report and Review of the Literature. Strahlentherapie und Onkologie, 185, 198-201.
https://doi.org/10.1007/s00066-009-1925-8
[9]
Mentzel, T. (2001) Myofibroblastic Sarcomas: A Brief Review of Sarcomas Showing a Myofibroblastic Line of Differentiation and Discussion of the Differential Diagnosis. Current Diagnostic Pathology, 7, 17-24.
https://doi.org/10.1054/cdip.2000.0057
[10]
Chan, J.Y., Gooi, Z., Wong, E.W., Ng, S.K., Tong, M.C. and Vlantis, A.C. (2017) Low-Grade Myofibroblastic Sarcoma: A Population-Based Study. Laryngoscope, 127, 116-121. https://doi.org/10.1002/lary.26146
