In
recent years Copper-64 in the chemical form of copper chloride ([64Cu]CuCl2)
has been identified as a potential agent for PET imaging and radionuclide
therapy. The aim of this research was to determine the
biodistribution and the labeling of radio nanoparticle
with 64CuCl2, the nanoparticles Cu(acac)2/F-TiO2 were mixed with 64CuCl2 (20-37 MBq), then the final solution
was used to injected healthy Wistar rats to probe the absorption of nanoparticle
inside tissue trough
of the groups OH that are formed during the functionalization of the Cu(acac)2/F-TiO2.
The “in vivo” evaluation after realize the images study in micro PET equipment,
uptake of the radio-nanoparticle was observed in the digestive system in
the healthy Wistar rats.
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