In order to improve the concentration of selenium in the maifanite concentrate, the optimum experimental conditions were obtained by orthogonal experimentas follows: size of maifanite was 10 mesh, concentration of maifanite was 15 (expressed as the quality of maifanite divided by that of water), soaking time was 60 min at room temperature, heating temperature was 70oC, heating time was 20 min, pH value was 6. Under this condition, the concentrations of each element (ppm)determined by ICP-AES were: Fe 0.099, Cu 0.035, Mn 0.051, Zn 0.019, Se 0.028, Al 0.000.a ven in this document.
References
[1]
Loef, M., Schrauzer, G.N. and Walach, H. (2011) Selenium and Alzheimer’s Disease: A Systematic Review. Journal of Alzheimers Disease, 26, 81-104.
[2]
Ozcelik, D., Uzun, H. and Naziroglu, M. (2012) N-Acetylcysteine Attenuates Copper Overload-Induced Oxidative Injury in Brain of Rat. Biological Trace Element Research, 147, 292-298. https://doi.org/10.1007/s12011-012-9320-1
[3]
Takahashi, S., Takahashi, I., Sato, H., Kubota, Y., Yoshida, S. and Muramatsu, Y. (2001) Age-Related Changes in the Concentrations of Major and Trace Elements in the Brain of Rats and Mice. Biological Trace Element Research, 80, 145-158.
https://doi.org/10.1385/BTER:80:2:145
[4]
Koc, E.R., Ilhan, A., Zübeyde, A., Acar, B., Gürler, M., Altuntas, A., Karapirli, M. and Bodur, A.S. (2015) A Comparison of Hair and Serum Trace Elements in Patients with Alzheimer Disease and Healthy Participants. Turkish Journal of Medical Sciences, 45, 1034-1039. https://doi.org/10.3906/sag-1407-67
[5]
Juan, L., Zhang, P.Y., Gao, Y., Song, X.G. and Dong, J.H. (2008) Overview of Maifanshi: Its Physi-Chemical Properties and Nutritious Function in Drinking Water. Environmental Science & Technology, 31, 63-66.
[6]
Zhang, B.G. (2005) The Progress of Pharmaceutical Research on the Maifanite. Chinese Traditional Patent Medicine, 27, 1205-1208.
[7]
Jiang, L.F., Liao, H.L., Huang, H.M., Zhou, L.X., Li, L., Cheng, S.X. and Du, C.Z. (2013) Potential Prevention and Treatment of Maifanite for Alzheimer’s Disease Based on Behavior Test, Oxidative Stress Assay and Trace Element Analysis in Hippocampus of Abeta (25-35)-Induced AD Rats. Biological Trace Element Research, 152, 50-56. https://doi.org/10.1007/s12011-012-9590-7