Objectives:We retrospectively analyzed whether the severity of
Chronic Obstructive Pulmonary Disease (COPD) affected disease-specific survival in Non-Small-Cell Lung
Cancer (NSCLC) patients after surgical resection. Methods:We enrolled 210NSCLC patients who underwent curative surgery
between 2009 and 2011. Classification of COPD severity was based on guidelines
of the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Results:A total of 55 patients were diagnosed with COPD.The 5-year disease-specificsurvival of patients with COPD was not different
compared with that of patients without COPD. Among the COPD patients, 40 were
classified as GOLD 1, 13 as GOLD 2, and 2 as GOLD 3. Although the number of patients
with GOLD 2-3 was small, the 5-year disease-specificsurvival of patients with GOLD 2-3 was
significantly poorer. We found the prognostic significance of GOLD 2-3 in
univariate analysis, but
failed to find this in multivariate analysis. Conclusions:There is a possibility that the severity of COPD
might be useful to predict the prognosis of NSCLC patients.
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