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Epidemiological Profile of Chronic Kidney Disease at the General Hospital of National Reference of N’Djamena (Chad)

DOI: 10.4236/ojneph.2016.63010, PP. 78-85

Keywords: Chronic Kidney Disease, Epidemiology, N’djamena, Chad

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Abstract:

Introduction: Chronic renal failure is a disease that affects many patients worldwide and increasingly in Africa. At the end of 2003, about 1.1 million people were suffering from End-Stage Renal Disease (ESRD) and were treated with periodic dialysis [12]. In Africa, CKF represents 2% to 10% of hospital admissions and is responsible for 4% to 22% of deaths [14]. So, this study is conducted for the first time in Chad, with the aims to determine the prevalence of CKD. Methods: This was a retrospective, descriptive and analytical study over a period of 12 months from April 29, 2011 to April 28, 2012. All patients with chronic renal failure regardless of etiology and stage of chronic kidney disease were included in the study. Chronic renal failure was defined as a glomerular filtration rate below 60 ml/min/1.73m (MDRD) for more than 3 months. This study was conducted in several departments of the National General Reference Hospital (NGRH) of N’Djamena. Result: Among 2039 inpatients, 195 patients had chronic renal failure, as a frequency of 9.6%. The average age of our patients was 51 ± 16.8 years, ranging from 11 to 85 years. Male predominance was noted to be 59% of men against 41% of women. We noted that high blood pressure accounted for 66.2% (N = 129) of cases, diabetes in 48.2% (N = 94), alcoholism in 28.7% (N = 56), smoking in 14.9% (N = 29) and the association alcoholism-smoking in 19.5% (N = 38). Hypertension was the leading cause of chronic renal failure (66.2%). All patients had a serum creatinine and creatinine clearance was assessed. Among them, we noted 57 patients (29%) with end-stage renal failure. The average calcium and phosphate serum were 1.8 mmol/l and 1.6 mmol/l, respectively. We noted that 120 patients as 61.5%, currently took herbal medicine. 48 out of 57 of our patients with ESRD as 24.6% of patients in the study had received replacement therapy (hemodialysis) with 12.5% of deaths. Conclusion: Chad, who compiled the first study with 195 patients at the General Hospital of N’Djamena National Reference over a period of one year has objectified a prevalence of chronic renal failure of 9.6%.

References

[1]  Jacquelinet, C. and Briançon, S. (2005) Epidemiological and Information Network in Nephrology (Rein): A National Register of Replacement Treatments for Chronic Renal Insufficiency. Bulletin Epidémiologique Hebdomadaire, 37-38.
[2]  Said, K., et al. (2013) Troubles minéraux et osseux de la maladie rénale chronique (TMO-MRC). Revue Francophone des Laboratoires, 29, 455.
[3]  Fouque, D., et al. (2010) Evolution de la prise en charge de la maladie osseuse et minérale des patients hémodialysés en France entre juin 2005 et juin 2008. Néphrologie & Thérapeutique, 6, 11-20.
[4]  Young, E.W., et al. (2005) Predictors and Consequences of Altered Mineral Metabolism: The Dialysis Outcomes and Practice Patterns Study. Kidney International, 67, 1179-1187.
http://dx.doi.org/10.1111/j.1523-1755.2005.00185.x
[5]  Diouf, B., Niang, A., Ka, E.F., Badiane, M. and Moreira, D.T. (2003) Chronic Renal Failure in One Dakar Hospital Department. Dakar Medical, 48, 185-188.
[6]  Yassine, D. (2012) Prise en charge de l’insuffisance rénale chronique terminale en urgence. Thèse Med, Maroc, Fès, 98.
[7]  Jarraya, F., Mafouch, Chaibou, L., Yaich, S., Kammoun, K., Kharrat, M., Mrabet, S., Ben Hmid, M., Charfeddine, K. and Hachicha, J. (2008) Prise en charge de l’anémie chez l’hémodialysé en Tunisie. Néphrologie, CHU Hedi-Chaker, Sfax Tunisie. Néphrologie & Thérapeutique, 4, 517.
[8]  United States Renal Data System 2010 Annual Data Report.
[9]  Masse, V., Richard, J.B. and Landais, P. (2009) Epidémiologie de l’insuffisance rénale chronique traitée par dialyse.
[10]  Berland, Y. and Dussol, B. (2003) Néphrologie pour l’interne, Tome 4. Elsevier, Paris, 386.
[11]  Raharivelina, C. and Andriamanantsoa, L. (2004) Insuffisance rénale chronique: La prévention est primordiale dans les pays en développement comme Madagascar. Médecine d’Afrique Noire, 15, 245-246.
[12]  Ouattara, B., Kra, O., Diby, K., Thot’o, A.S., Ouattara, I. and Ndri, N. (2004) Insuffisance rénale chronique chez l’adulte au CHU de Bouaké. Afr Biomed, 9, 66-70.
[13]  Lagoud, D.A., Ackoundoun, N.K.C., Tchicaya, A.F., et al. (2008) Réinsertion profesionnelle et scolaire des patients atteints d’insuffisance rénale chronique et traités par hémodialyse en Côte d’Ivoire. Médecine d’Afrique Noire, 55, 259-264.
[14]  Benamar, L., Rhou, H., Guerraoui, M.H., Bakkal, B., Benjelloun, H., Laoud, I., et al. (2003) Cardiovascular Calcifications in Hemodialysis Patients. Prevalence and Risk Factors. Nephrologie, 24, 143-147.

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