全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Periodontitis and Inflammation: Plasma High Titer Naturally Occurring Anti-Glucan Antibodies Form Immune Complex with Streptococcus mutans Antigen

DOI: 10.4236/mri.2016.53005, PP. 45-54

Keywords: Streptococcus mutans, Anti-β-Glucan Antibody (ABG), Dextran Binding Immunoglobulins (DIg), Immune Complexes

Full-Text   Cite this paper   Add to My Lib

Abstract:

Atheromatous plaques usually contain antigens of the periodontitis-causing bacteria Streptococcus mutans though molecular mechanism of this incorporation remains unknown. Since vascular adhesion and inflammatory potential of Immune Complexes (IC) are known we investigated the naturally occurring plasma antibodies that recognize major antigens from S. mutans. S. mutans-binding plasma proteins (SMBP) prepared by affinity chromatography on a column of heat-killed S. mutans could recognize α- and β

References

3GalNAc-) Is Far Superior to Non-Repeating N-Acetyl Lactosamine as Ligand. International Journal of Biological Macromolecules, 35, 269-276.
http://dx.doi.org/10.1016/j.ijbiomac.2005.03.004
-->
[1]  McGhie, D., Hutchison, J.G., Nye, F. and Ball, A.P. (1977) Infective Endocarditis Caused by Streptococcus mutans. British Heart Journal, 39, 456-458.
http://dx.doi.org/10.1136/hrt.39.4.456
[2]  Nakano, K., Inaba, H., Nomura, R., et al. (2006) Detection of Cariogenic Streptococcus mutans in Extirpated Heart Valve and Atheromatous Plaque Specimens. Journal of Clinical Microbiology, 44, 3313-3317.
http://dx.doi.org/10.1128/JCM.00377-06
[3]  Southerland, J.H., Taylor, G.W. and Offenbacher, S. (2005) Diabetes and Periodontal Infection: Making the Connection. Clinical Diabetes, 23, 171-178.
http://dx.doi.org/10.2337/diaclin.23.4.171
[4]  Kojima, A., Nakano, K., Wada, K., et al. (2012) Infection of Specific Strains of Streptococcus mutans, Oral Bacteria, Confers a Risk of Ulcerative Colitis. Scientific Reports, 2, 332.
http://dx.doi.org/10.1038/srep00332
[5]  Mozaffarian, D., Wilson, P.W.F. and Kannel, W.B. (2008) Beyond Established and Novel Risk Factors: Lifestyle Risk Factors for Cardiovascular Disease. Circulation, 117, 3031-3038.
http://dx.doi.org/10.1161/CIRCULATIONAHA.107.738732
[6]  De Nardin, E. (2001) The Role of Inflammatory and Immunological Mediators in Periodontitis and Cardiovascular Disease. Annals of Periodontology, 6, 30-40.
http://dx.doi.org/10.1902/annals.2001.6.1.30
[7]  Reisfeld, R.A., Lewis, U.J. and Williams, D.E. (1962) Disk Electrophoresis of Basic Proteins and Peptides on Polyacrylamide Gels. Nature, 195, 281-283.
http://dx.doi.org/10.1038/195281a0
[8]  Ogden, R.C. and Adams, D.A. (1987) Electrophoresis in Agarose and Acrylamide Gels. Methods in Enzymology, 152, 61-87.
http://dx.doi.org/10.1016/0076-6879(87)52011-0
[9]  Paul, A., Antony, M., Mathai, J. and Appukuttan, P.S. (2011) High Polymeric IgA Content Facilitates Recognition of Microbial Polysaccharide-Natural Serum Antibody Immune Complexes by Immobilized Human Galectin-1. Immunology Letters, 136, 55-60.
http://dx.doi.org/10.1016/j.imlet.2010.12.004
[10]  Laemmli, U.K. (1970) Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4. Nature, 227, 680-685.
http://dx.doi.org/10.1038/227680a0
[11]  Paul, A., Geetha, M., Chacko, B.K. and Appukuttan, P.S. (2009) Multiple Specificity of Human Serum Dextran- Binding Immunoglobulin: α (1→6)- and β (1→3)-Linked Glucose and α (1→3)-Linked Galactose in Natural Glycoconjugates Are Recognized. Immunological Investigations, 38, 153-164.
http://dx.doi.org/10.1080/08820130902729629
[12]  Geetha, M., Annamma, K.I., Mathai, J. and Appukuttan, P.S. (2007) Normal Human Plasma Anti-Beta-Glucoside Antibody Has Markedly Elevated IgA Content and Binds Fungal and Yeast Polysaccharides. Immunological Investigations, 36, 73-83.
http://dx.doi.org/10.1080/08820130600745737
[13]  Mandagini, G., Subramanian, S.P., Vasantha, K. and Appukuttan, P.S. (2013) Human Plasma Anti-α-Galactoside Antibody Forms Immune Complex with Autologous Lipoprotein (a). Immunological Investigations, 42, 324-340.
http://dx.doi.org/10.3109/08820139.2013.764316
[14]  Baues, R.J. and Gray, G.R. (1977) Lectin Purification on Affinity Columns Containing Reductively Aminated Disaccharides. Journal of Biological Chemistry, 252, 57-60.
[15]  Weir, D.M. (1986) Handbook of Experimental Immunology. Blackwell Scientific Publications, Oxford; Boston.
[16]  Bradford, M.M. (1976) A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding. Analytical Biochemistry, 72, 248-254.
http://dx.doi.org/10.1016/0003-2697(76)90527-3
[17]  Chia, J.S., Chang, W.C., Yang, C.S. and Chen, J.Y. (2000) Salivary and Serum Antibody Response to Streptococcus mutans Antigens in Humans. Oral Microbiology and Immunology, 15, 131-138.
http://dx.doi.org/10.1034/j.1399-302x.2000.150210.x
[18]  Epstein, S.E. (2002) The Multiple Mechanisms by Which Infection May Contribute to Atherosclerosis Development and Course. Circulation Research, 90, 2-4.
[19]  Morré, S.A., Stooker, W., Lagrand, W.K., van den Brule, A.J.C. and Niessen, H.W.M. (2000) Microorganisms in the Aetiology of Atherosclerosis. Journal of Clinical Pathology, 53, 647-654.
http://dx.doi.org/10.1136/jcp.53.9.647
[20]  Erickson, P.R. and Herzberg, M.C. (1993) The Streptococcus sanguis Platelet Aggregation-Associated Protein. Identification and Characterization of the Minimal Platelet-Interactive Domain. The Journal of Biological Chemistry, 268, 1646-1649.
[21]  Sangeetha, S.R. and Appukuttan, P.S. (2005) IgA1 Is the Premier Serum Glycoprotein Recognized by Human Galectin-1 Since T Antigen (Galbeta1-->3GalNAc-) Is Far Superior to Non-Repeating N-Acetyl Lactosamine as Ligand. International Journal of Biological Macromolecules, 35, 269-276.
http://dx.doi.org/10.1016/j.ijbiomac.2005.03.004
[22]  Jayakumari, A.N. and Appukuttan, P.S. (2008) IgA1 Desialylated by Microbial Neuraminidase Forms Immune Complex with Naturally Occurring Anti-T Antibody in Human Serum. Immunology Letters, 115, 90-97.
http://dx.doi.org/10.1016/j.imlet.2007.10.005
[23]  Novak, R., Dabelic, S. and Dumic, J. (2012) Galectin-1 and Galectin-3 Expression Profiles in Classically and Alternatively Activated Human Macrophages. Biochimica et Biophysica Acta, 1820, 1383-1390.
http://dx.doi.org/10.1016/j.bbagen.2011.11.014
[24]  Bian, C.-F., Zhang, Y., Sun, H., Li, D.-F. and Wang, D.-C. (2011) Structural Basis for Distinct Binding Properties of the Human Galectins to Thomsen-Friedenreich Antigen. PLoS ONE, 6, e25007.
http://dx.doi.org/10.1371/journal.pone.0025007
[25]  Pussinen, P.J., Nyyss?nen, K., Alfthan, G., Salonen, R., Laukkanen, J.A. and Salonen, J.T. (2005) Serum Antibody Levels to Actinobacillus actinomycetemcomitans Predict the Risk for Coronary Heart Disease. Arteriosclerosis Thrombosis and Vascular Biology, 25, 833-838.
http://dx.doi.org/10.1161/01.ATV.0000157982.69663.59
[26]  Kauffmann, R.H., Herrmann, W.A., Me?er, C.J., Daha, M.R. and van Es, L.A. (1980) Circulating IgA-Immune Complexes in Henoch-Sch?nlein Purpura. A Longitudinal Study of Their Relationship to Disease Activity and Vascular Deposition of IgA. American Journal of Medicine, 69, 859-866.
http://dx.doi.org/10.1016/S0002-9343(80)80011-8
[27]  Hall, R.P. and Lawley, T.J. (1985) Characterization of Circulating and Cutaneous IgA Immune Complexes in Patients with Dermatitis Herpetiformis. Journal of Immunology, 135, 1760-1765.
[28]  Mayadas, T.N., Tsokos, G.C. and Tsuboi, N. (2009) Mechanisms of Immune Complex-Mediated Neutrophil Recruitment and Tissue Injury. Circulation, 120, 2012-2024.
http://dx.doi.org/10.1161/CIRCULATIONAHA.108.771170
[29]  Li, X., Kolltveit, K.M., Tronstad, L. and Olsen, I. (2000) Systemic Diseases Caused by Oral Infection. Clinical Microbiology Reviews, 13, 547-558.
http://dx.doi.org/10.1128/CMR.13.4.547-558.2000

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133