Purpose: To compare the demographic data and outcomes of younger versus elderly
patients with acute coronary syndromes. Methods: This was a retrospective data bank
analysis study with 966 patients (268 in the younger group (less than 55 years) and
698 in the elderly group (more than 55 years)). Data were obtained about clinical
characteristics, angiography, and medication used at hospital and coronary definitive
treatment. The primary endpoint was all cause of in-hospital death and combined
events. Comparison between groups was made by Anova and Q-square. Multivariative
analysis was determined by logistic regression and was considered significative
when p < 0.05. Long-term mortality and combined events were studied using Kaplan-
Meyer curves with median follow-up of 11.21 months. Results: The median age in the
younger group was 48 years versus 69 years in the elderly group. In the younger
group 26% was ST-myocardial infarction versus 18% in the elderly group. About 7%
of younger patients were submitted to coronary bypass surgery and 42% to percutaneous
coronary angioplasty versus 12% and 25% in elderly group, respectively. Significant
difference was observed between the younger versus elderly groups in deaths
(1.5% × 7.5%, p = 0.004), combined events (14.9% × 26.3%, p = 0.02) and killip III/IV
(3.7% × 8.3%, p = 0.04). Long-term mortality was 3.7% × 10.2%, p = 0.01). Conclusions:
In patients with acute coronary syndromes age was an important predictor
factor of mortality and complications. Significative differences in outcomes were observed
between the two groups in-hospital and long-term follow-up.
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