The Electrophysiological Memory Function of Hippocampus Different from O’Keefe and Mosers

The electrophysiology of hippocampus demonstrated by O’Keefe and Mosers is yet unattainable to explain the same memory function of mammillary bodies. The limbic-reticular coupling theory I proposed previously suggested the descending limbic system regulate the ascending reticular systems to consolidate and recall declarative memories. On electrophysiology, the hippocampal CA3 neurons can regulate the raphe nuclei and ventral tegmental area in their activities, while the cholinergic-mediated gamma wave is also coupled to theta activities. In this way, through these limbic-reticular electrophysiological couplings, the hippocampus can synchronously recall several components of a memory dispersed in various cortical areas. Therefore, here is outlined the alternative part of hippocampal electrophysiology on memory recall different from O’Keefe and Mosers.