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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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针刺治疗Graves'眼病患者突眼的免疫学机制探讨
Keywords: Grave' ophthalmopathy, acupuncture, ADCC
Abstract:
目的 观察针刺治疗Graves'眼病(Graves' ophthalmopathy,GO)患者突眼症状疗效,以及患者血清对抗体依赖细胞介导的细胞毒(ADCC)作用的影响。方法 将54例GO患者随机分为三组,其中针药Ⅰ组18例,针药Ⅱ组18例,对照组18例,观察不同穴位组方结合他巴唑对突眼度的影响,并采用乳酸脱氢酶(LDH)释放试验,观察治疗前后患者血清对培养的人眼外肌细胞的ADCC作用。结果 针药Ⅱ组治疗突眼有效率高于针药I组(P<0.05),对照组与针药治疗组比较差异均有显著性意义(P<0.01)。治疗后GO患者血清对眼外肌的ADCC作用较针刺前明显降低,且针药Ⅱ组低于对照组(P<0.05)。结论 针刺对GO眼病患者突眼的治疗作用可能与减轻血清对眼外肌的ADCC损伤过程有关；针刺远近配穴对抗眼肌损伤的免疫调节作用优于单纯局部取穴
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