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OALib Journal期刊
ISSN: 2333-9721
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micrornas对一碳单位代谢的调控及相应生物学过程的影响
Keywords: 一碳单位代谢,micrornas,dna甲基化,调控
Abstract:
？一碳单位代谢(ocm)是生物体一碳单位即甲基基团从供体化合物转移到受体的过程,对dna合成和dna甲基化至关重要。micrornas(mirnas)是一类约为22个核苷酸的内源非编码rna,能够通过与靶mrna特异性结合而导致靶mrna降解或抑制其蛋白的翻译。mirnas通过调节转录后水平来调控基因的表达并参与后续的生物学过程,在一碳单位代谢和相应生物学过程中发挥着重要作用。本文阐述了mirnas在一碳单位代谢中的作用及其研究进展。
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