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OALib Journal期刊
ISSN: 2333-9721
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邻苯二甲酸酯类化合物的生殖毒性及其环境内分泌干扰效应
Keywords: 增塑剂,生殖毒性,内分泌干扰效应,邻苯二甲酸酯
Abstract:
？邻苯二甲酸酯类(paes)增塑剂是广泛存在于人类生活环境中的化合物之一。由于其环境内分泌干扰效应受到全球相关领域的高度关注。它经过食物链进入人体并蓄积在体内,影响人类生殖健康,对生殖、发育、激素分泌以及基因表达造成损害。目前的研究表明,paes可引起生殖能力受损,并对后代发育产生影响。且paes通过内分泌干扰效应,干扰体内相关激素的分泌与功能,其在血液和尿液中的代谢物与糖尿病的发生密切相关。因此,本文主要对paes的生殖毒性及其环境内分泌干扰效应的研究进展作一综述。
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