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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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镁合金表面的仿生修饰及抑菌性能的研究
Keywords: 材料表面与界面,季铵盐,涂层,抑菌性能
Abstract:
？用2,3--环氧丙基三甲基氯化铵对壳聚糖进行改性,合成了两种不同取代度(ds:29%,48%)的壳聚糖季铵盐,通过ftir、hnmr表征以证实其分子结构。用仿生共沉积法,在模拟体液中添加两种不同取代度的壳聚糖季铵盐,在镁合金az91表面修饰了一层薄的仿生涂层。sem和xrd对涂层分析表明:经仿生修饰后的镁合金表面为含有钙磷盐/壳聚糖季铵盐的复合涂层,涂层晶体构型不同。抑菌实验结果表明：与含有钙磷盐/壳聚糖的复合涂层样品相比,含有钙磷盐/壳聚糖季铵盐的复合涂层对金黄色葡萄球菌具有明显的抑菌作用；比浊法测定显示：对金黄色葡萄球菌作用6h,四种含有不同量的壳聚糖季铵盐样品均具有较好的抑菌效果,抑菌率为90%以上；作用24h的结果表明,模拟体液中添加较低浓度的壳聚糖季铵盐制备的样品抑菌效果较好,抑菌率为98%。
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