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OALib Journal期刊
ISSN: 2333-9721
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聚己内酯的表面光化学接枝改性以及细胞相容性
Keywords: 聚己内酯,基丙烯酸,化学接枝,皮细胞
Abstract:
？采用紫外光氧化接枝的方法将亲水性的聚甲基丙烯酸（pmaa）接枝到聚己内酯(pcl)表面，用水溶性碳化二亚胺——1-二甲基胺丙基-3-乙基碳化二亚胺作为缩合剂在接枝膜表面固定了明胶，并用衰减全反射红外光谱（atr-ftir）和光电子能谱（xps）对其表面进行了表征。测量了水相动态接触角,研究了测试细胞相容性.结果表明，经过改性后的pcl膜表面的亲水性显著提高，内皮细胞在改性pcl表面上培养96h后的细胞增殖率和活性均有明显提高。
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