|
OALib Journal期刊
ISSN: 2333-9721
费用：99美元
|
|
|
|
非胶原蛋白模拟多肽e8ds促进i型胶原仿生矿化
Keywords: 有机高分子材料,生物矿化,非胶原蛋白,胶原纤维,多肽
Abstract:
？通过分析骨涎蛋白和牙本质基质蛋白的功能域,设计合成了一种非胶原蛋白模拟多肽e8ds(eeeeeeeedsesseedr),引入胶原蛋白仿生矿化体系,共同调控磷酸钙晶体的矿化过程。圆二色谱和红外光谱分析结果表明,多肽e8ds可与钙离子和胶原分子通过静电作用相结合。使用稳态凝胶系统对多肽e8ds的分析结果表明,e8ds具有很强的调控钙磷盐矿化的能力。多肽的加入有助于胶原纤维的分子组装,增加了形核位点,促进了磷酸钙在胶原纤维表面矿化,使胶原纤维的矿化程度明显提高。
| [1] | 1g.he,a.george,dentinmatrixprotein1immobilizedontypeicollagenfibrilsfacilitatesapatitedepositioninvitro,journalofbiologicalchemistry,279(12),11649(2004)
|
| [2] | 2r.fujisawa,y.nodasaka,y.kuboki,furthercharacterizationofinteractionbetweenbonesialoprotein(bsp)andcollagen,calcifiedtissueinternational,56(2),140(1995)
|
| [3] | 3c.e.tye,g.k.hunter,h.a.goldberg,identificationofthetypeicollagen-bindingdomainofbonesialoproteinandcharacterizationofthemechanismofinteraction,journalofbiologicalchemistry,280(14),13487(2005)
|
| [4] | 4j.j.hao,a.ramachandran,a.george,temporalandspatiallocalizationofthedentinmatrixproteinsduringdentinbiomineralization,journalofhistochemistry&cytochemistry,57(3),227(2009)
|
| [5] | 5s.weiner,w.traub,h.d.wagner,lamellarbone:structure-functionrelations,journalofstructuralbiology,126(3),241(1999)
|
| [6] | 6w.zhang,s.s.liao,f.z.cui,hierarchicalself-assemblyofnano-fibrilsinmineralizedcollagen,chemistryofmaterials,15(16),3221(2003)
|
| [7] | 7j.h.kinney,s.habelitz,s.j.marshall,g.w.marshall,theimportanceofintrafibrillarmineralizationofcollagenonthemechanicalpropertiesofdentin,journalofdentalresearch,82(12),957(2003)
|
| [8] | 8s.x.xiao,c.yu,x.m.chou,w.j.yuan,y.wang,l.bu,g.fu,m.q.qian,j.yang,y.z.shi,l.d.hu,b.han,z.m.wang,w.huang,j.liu,z.chen,g.p.zhao,x.y.kong,dentinogenesisimperfecta1withorwithoutprogressivehearinglossisassociatedwithdistinctmutationsindspp,naturegenetics,27(2),201(2001)
|
| [9] | 9r.srinivasan,b.chen,j.p.gorski,a.george,recombinantexpressionandcharacterizationofdentinmatrixprotein1,connectivetissueresearch,40(4),251(1999)
|
| [10] | 11r.m.wazen,c.e.tye,h.a.goldberg,g.k.hunter,c.e.smith,a.nanci,invivofunctionalanalysisofpolyglutamicaciddomainsinrecombinantbonesialoprotein,journalofhistochemistry&cytochemistry,55(1),35(2007)
|
| [11] | 10a.george,a.veis,phosphorylatedproteinsandcontroloverapatitenucleation,crystalgrowth,andinhibition,chemicalreviews,108(11),4670(2008)
|
| [12] | 12n.l.harris,k.r.rattray,c.e.tye,t.m.underhill,m.j.somerman,j.a.d’errico,a.f.chambers,hg.k.unter,h.a.goldberg,functionalanalysisofbonesialoprotein:identificationofthehydroxyapatitenucleatingandcell-bindingdomainsbyrecombinantpeptideexpressionandsite-directedmutagenesis,bone,27(6),795(2000)
|
| [13] | 13d.iejima,t.saito,t.uemura,acollagen-phosphophorynspongeasascaffoldforbonetissueengineering,journalofbiomaterialsscience-polymeredition,14(10),1097(2003)
|
| [14] | 14f.r.tay,d.h.pashley,guidedtissueremineralisationofpartiallydemineralisedhumandentine,biomaterials,29(8),1127(2008)
|
| [15] | 15e.k.girija,y.yokogawa,f.nagata,apatiteformationoncollagenfibrilsinthepresenceofpolyacrylicacid,journalofmaterialsscience-materialsinmedicine,15(5),593(2004)
|
| [16] | 16g.d.pins,d.l.christiansen,r.patel,f.h.silver,selfassemblyofcollagenfibers.influenceoffibrillaralignmentanddecorinonmechanicalproperties,biophysicaljournal,73(4),2164(1997)
|
| [17] | 17g.k.hunter,p.v.hauschka,a.r.poole,l.c.rosenberg,h.a.goldberg,nucleationandinhibitionofhydroxyapatiteformationbymineralizedtissueproteins,biochemicaljournal,317(1),59(1996)
|
| [18] | 18g.k.hunter,h.a.goldberg,nucleationofhydroxyapatitebybonesialoprotein,proceedingsofthenationalacademyofsciencesoftheunitedstatesofamerica,90(18),8562(1993)
|
| [19] | 19k.e.kadler,d.f.holmes,j.a.trotter,j.a.chapman,collagenfibrilformation,biochemicaljournal,316(1),1(1996)
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|
