OALib Journal期刊
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雪灵芝不同提取物的生物活性
DOI: 10.3724/SP.J.1145.2010.00642, PP. 642-645
Keywords: 雪灵芝,水提物,醇提物,口服液,生物活性
Abstract:
采用蛋白酪氨酸磷酸酯酶(ptp1b)、二肽基肽酶(dpp-iv)、α-葡萄糖苷酶-rat(α-glucosidase-rat)、mcf-7/adr肿瘤耐药细胞增敏、肿瘤细胞毒活性(hepg2肝癌细胞)、骨髓有核细胞增殖等模型,对雪灵芝水提物、醇提物和市售的雪灵芝营养口服液分别进行体外免疫调节、抗肿瘤、糖尿病等活性筛选.结果表明:雪灵芝水提物、醇提物和营养口服液均对蛋白酪氨酸磷酸酯酶/ptp1b模型呈阳性,对其余5种模型呈阴性,说明蛋白酪氨酸磷酸酯酶(ptp1b)模型可以作为雪灵芝有效部位的活性跟踪模型.表6参16
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