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OALib Journal期刊
ISSN: 2333-9721
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趋磁细菌磁小体形成机制研究进展
DOI: 10.3724/SP.J.1145.2012.00157, PP. 157-162
Keywords: 趋磁细菌,磁小体,形成机制,生物矿化
Abstract:
磁小体（magnetosome）是由趋磁细菌（magnetotacticbacteria，mtb）体内合成并有生物膜包裹的纳米级磁性晶体，其形成过程是一个包括多种基因和蛋白参与并且受基因表达调控的酶催化过程.本文主要从铁离子吸收、磁小体膜形成、铁离子转运、生物矿化和磁小体链组装等5个方面来详细阐述磁小体的形成过程，重点介绍近年来分离和鉴定的相关基因和蛋白，并分析其在磁小体形成过程中的作用机制，同时还介绍了氧气、铁源和培养基成分等环境因素对磁小体形成的影响.尽管已经鉴别了大部分磁小体形成的相关基因，但是运用遗传学和生化分析手段阐明其作用机理仍然是一个挑战.磁小体形成机制的进一步研究和阐明将为其在生物技术领域的应用奠定基础.图1参37
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