|
OALib Journal期刊
ISSN: 2333-9721
费用：99美元
|
|
|
|
超微七味白术散与酵母菌协同治疗小鼠菌群失调腹泻
DOI: 10.3724/SP.J.1145.2013.10002, PP. 61-67
Keywords: 超微七味白术散,酵母菌,菌群失调,肠道微生物,肠道酶
Abstract:
探讨超微七味白术散与酵母菌联用对菌群失调腹泻的疗效，可为超微七味白术散与酵母菌配伍制剂的研发提供依据.采用抗生素建立小鼠菌群失调腹泻模型，灌胃给药七味白术散50%量超微汤药、50%量超微汤药＋12.5%量酵母、25%量超微汤药＋25%量酵母、12.5%量超微汤药＋50%量酵母及全量酵母，比较分析小鼠体重变化率、免疫器官指数、肠道菌群数及酶活.结果表明，超微七味白术散和酵母菌对小鼠体重和脾脏无显著影响，各治疗组的胸腺指数为正常水平（p>0.05）；超微七味白术散和酵母菌均能促进双歧杆菌和乳酸菌的生长（p<0.01），调节微生态平衡；50%量超微汤药组和25%量超微汤药＋25%量酵母组的大肠杆菌、细菌数恢复至正常水平（p>0.05）.治疗后肠道内纤维素酶活性均恢复至正常组（对照）水平（p>0.05）；50%量超微汤药＋12.5%量酵母组和25%量超微汤药＋25%酵母量组的淀粉酶活性恢复至正常水平（p>0.05）；木聚糖酶、蛋白酶活性与超微饮片的浓度及酵母菌的量有一定的关系，但均未达到正常组水平（p<0.05）.说明七味白术散25%量超微汤药＋25%量酵母配伍能够有效治疗菌群失调小鼠腹泻，其效果与超微七味白术散50%量相当，达到全量传统汤剂的效果.
| [1] | 1杨光文.七味白术散治疗小儿腹泻42例临床观察[j].中国社区医师,2009,25(14):39[yanggw.qiweibaizhusanpowdertreatmentof42casesofdiarrheainchildren[j].chincommunitydoctors,2009,25(14):
|
| [2] | 2李刚.七味白术散加减治疗小儿霉菌性肠炎48例[j].陕西中医,2009,30(3):322-323[lig.effectofqiweibaizhusanpowderonthetreatmentoffungienteritisin48childrenpatients[j].shanxijtradchinmed,2009,30(3):322-
|
| [3] | 3李纪三.七味白术散加减治疗溃疡性结肠炎[j].医药论坛杂志,2009,30(12):96-97[lijs.effectofqiweibaizhusanpowderonthetreatmentofulcerativecolitis[j].jmedforum,2009,30(12):96-
|
| [4] | 4刘双英.七味白术散治疗小儿脾虚湿盛型腹泻120例[j].陕西中医,2009,30(10):1331-1332[lisy.effectofqiweibaizhusanpowderonthetreatmentofpediatricspleendampnesstypediarrheain120childrenpatients[j].shanxijtradchinmed,2009,30(10):1331-
|
| [5] | 5李春颖.七味白术散加味治疗抗生素相关性腹泻疗效观察[j].中日友好医院学报,2010,24(5):292-293[licy.qiweibaizhupowdermodifiedtreatmentofantibiotic-associateddiarrheaoutlook[j].sino-jpnfriendship,2010,24(5):292-
|
| [6] | 6谭周进,吴海,刘富林,蔡莹,蔡光先,张华玲,曾奥.超微七味白术散对肠道微生物及酶活性的影响[j].生态学报,2012,32(21):6856-6863[tanzj,wuh,liufl,caiy,caigx,zhanghl,zenga.effectofultra-micropowderqiweibaizhusanontheintestinalmicrobiotaandenzymeactivitiesinmice[j].actaecolsin,2012,32(21):6856-
|
| [7] | 7王文建.国内儿科微生态制剂的临床应用[j].中国实用儿科杂志,2010,25(7):557-559[wangwj.domesticpediatricclinicalapplicationofprobiotics[j].chinjpracticalpediatrics,2010,25(7):557-
|
| [8] | 8王定昌.浅谈食品酵母的营养与生产应用[j].粮油食品科技,2010,18(2):65-67[wangdc.onthenutritionofthefoodyeastandproductionapplications[j].cerealsoilsfoodscitechnol,2010,18(2):65-
|
| [9] | 9giuseppel,antonioi,francon.effectivenessofaureobasidumpullulansandcandidaoleophilaagainstpostharveststrawberryrots[j].postharvestbioltechnol,1997,10(2):169-178
|
| [10] | 10ohnsons,sypurawd,gerdingdn.selectiveneutralizationofabacterialenterotoxinbyserumimmunoglobulinainresponsetomucosaldisease[j].infectimmun,1995,63(8):3166-3173
|
| [11] | 11施安辉.益生菌制剂的主要类群、作用机理及应用[j].中国饲料添加剂,2009,92(3):1-4[shiah,themaingroupsofprobiotics,mechanismsandapplications[j].chinafeedaddition,2009,92(3):1-
|
| [12] | 12梁金花,李荣辉,夏燕杰.中药微生态调节剂的发展现状与展望[j].中医研究,2012,25(10):78-80[liangjh,lirh,xiayj.microbialmodulatorcurrentdevelopmentofchinesemedicineandprospects[j].chinmedres,2012,25(10):78-
|
| [13] | 13王威,杨强.微生态制剂及其临床应用和研究进展[j].临床消化病杂志,2010,22(1):58-61[wangw,yangq.progressanditsclinicalapplicationofprobiotics[j].jclingastroenterol,2010,22(1):58-
|
| [14] | 14王君.微生态制剂研究进展与应用现状[j].现代畜牧兽医,2007(1):58-60[wangj.researchprogressandapplicationofprobiotics[j].modanimhusbandryvet2007(1):58-
|
| [15] | 15丁柯,倪学勤,潘康成.中草药和乳酸杆菌合生元的研究[j].中国家禽,2003,25(2):12-13[dingk,nixq,pankc.chineseherbalmedicineresearchandlactobacillussynbiotics[j].chinpoultry,2003,25(2):12-
|
| [16] | 22沈萍,陈向东.微生物学实验[m].4版.北京:高等教育出版社,2008[shenp,chenxd.microbiology[m].beijing:highereducationpress,
|
| [17] | 23贺石林,王键,王净净.中医科研设计与统计学[m].长沙:湖南科学技术出版社,2006:48-49[hesl,wangj,wangjj.tcmresearchdesignandstatistical[m].changsha:hunanscienceandtechnologypress,2006:48-
|
| [18] | 24赵斌,何绍江.微生物学实验[m].北京:科学出版社,2002[zhaob,hesj.microbiology[m].beijing:sciencepress,
|
| [19] | 25林清华.免疫学实验[m].武汉:武汉大学出版社,1999[linqh.experimentalimmunology[m].wuhan:wuhanuniversitypress,
|
| [20] | 30王慕逖.儿科学[m].5版.北京:人民卫生出版社,2000:265[wangmq.pediatrics[m].beijing:people’shealthpublishinghouse,2000:
|
| [21] | 35张爱忠,卢德勋,姜宁,高民,胡红莲.酵母培养物对绒山羊机体抗氧化能力的影响[j].动物营养学报,2010,22(3):781-786[zhangaz,ludx,jiangn,gaom,huhl.effectsofyeastonantioxidantabilityincashmeregoats[j].chinjanimnutr,2010,22(3):781-
|
| [22] | 16刘志恒.现代微生态学[m].北京:科学出版社,2002[liuzh.modernmicro-ecology[m].beijing:sciencepress,
|
| [23] | 17崔法新.中药加微生态制剂（金双歧）治疗对抗生素无效小儿细菌性痢疾55例疗效观察[j].新中医,2005,37(2):19-20[cuifx.treatmentofantibiotic-resistantbacillarydysenteryinchildrenbychineseherbalmedicineassociatedwithecologicpreparation:aclinicalobservationof55cases[j].newjtradchinmed,2005,37(2):19-
|
| [24] | 18邢广林,李同树,刘翠艳,苗静,张佰华.甘露寡糖、中药和微生态制剂对肉鸡抗氧化性能的影响[j].家畜生态学报,2007,28(1):47-51[xinggl,lits,liucy,miaoj,zhangbh.theeffectonchineseherbalmedicine,mannanoligoscharidex,microeconomicsonantioxidantcapabilityofbroilers[j].actaecolanimdomastici,2007,28(1):47-
|
| [25] | 19郭抗萧,周赛男,谭周进,蔡莹,佘颜,蔡光先.七味白术散对肠道酵母菌的抑促作用研究[j].现代生物医学进展,2013,13(27):5259-5263[guokx,zhousn,tanzj,caiy,shey,caigx.studyoninhibitionandboostingactionofqiweibaizhusantointestinalyeast[j].progrmodbiomed,2013,13(27):5259-
|
| [26] | 20陈梅枝,郭爱红.布拉酵母预防小儿肺炎激发腹泻疗效观察[j].山东医药,2010,50(9):97[chenmz,guoah.saccharomycesboulardiipreventpneumoniainchildrenwithdiarrheaexcitedefficacy[j].shandongpharm,2010,50(9):
|
| [27] | 21谭周进,张华玲,周赛男,余望贻,曾奥,蔡莹,蔡光先.菌群失调小鼠腹泻造模及超微中药干预过程中肠道微生物的变化[j].应用与环境生物学报,2013,19(3):449-453[tanzj,zhanghl,zhousn,yuwy,zenga,caiy,caigx.changeofintestinalmicrobesindysbacteriosis-modeledmicetreatedwithultra-micropowderofqiweibaizhusan[j].chinjapplenvironbiol,2013,19(3):449-
|
| [28] | 26朱俭,曹凯鸣,周润琦.生物化学实验[m].上海:上海科学技术出版社,1981[zhuj,caokm,zhourq.biochemicalexperiments[m].shanghai:shanghaiscienceandtechnologypress,
|
| [29] | 27郭抗萧,周赛男,曾奥,张华玲,吴海,谭周进.酵母菌的微生态调节作用[j].中国微生态学杂志,2013,25(1):94-103[guokx,zhousn,zenga,zhanghl,wuh,tanzj.microecologicalfunctionofyeast[j].chinjmicroecol,2013,25(1):94-
|
| [30] | 28lembckeb,kistm,lentzemj.antibiotic-associateddiarrhea:therapeuticaspectsandpracticalguidelines-aninter-disciplinaryapproachtoacommonproblem[j].schweizrundschmedprax,2003,92(17):809-816
|
| [31] | 29曹艳菊,张豫生,许连壮,米晓森,王惠.微生态制剂对抗生素相关性腹泻预防作用的研究[j].中华医院感染学杂志,2007,17(1):17-19[caoyj,zhangys,xulz,mixs,wangh.preventionofantibiotic-asociateddiarrheawithmicroecologicalmodulators[j].chinjnosocomiol,2007,17(1):17-
|
| [32] | 31王茂贵.微生态调节剂在儿科临床应用的评价[j].中国实用儿科杂志,2002,17(3):254[wangmg.micro-quarterstateregulatorsevaluatedinpediatricclinicalapplications[j].chinjpediatr,2002,17(3):
|
| [33] | 32罗先琼,符振华,陈少华,龙云,王伟光.微生态制剂治疗婴幼儿腹泻疗效观察[j].实用医学杂志,1995,11(8):541[luoxq,fuzh,chensh,longy,wangwg.probioticsefficacyoftreatmentofinfantilediarrhea[j].practicaljmed,1995,11(8):
|
| [34] | 33czeruckad,rampalp.experimentaleffectsofsaccharomycesboulardiiondiarrhealpathogens[j].microbesinfect,2002,4(7):733-739
|
| [35] | 34楚杰,刘可春,何秋霞,韩利文.酵母益生菌在单胃及反刍动物中的作用机制[j].中国畜牧兽医,2009,36(8):14-17[chuj,liukc,heqx,hanlw.yeastprobioticmechanismsinthestomachofruminantsinasingle[j].chinaanimhusbandryvet,2009,36(8):14-
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|
