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OALib Journal期刊
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昆虫orthodenticle基因研究进展
DOI: 10.3724/SP.J.1145.2010.00289, PP. 289-293
Keywords: orthodenticle基因,昆虫,胚胎发育,模式形成,头部分节
Abstract:
昆虫胚胎发育受一系列基因调控，这些基因按照时间、空间顺序启动或关闭，对胚胎细胞的生长和分化进行调节.orthodenticle（otd）是间隙基因，编码含同源结构域的转录因子，是昆虫胚胎发育的关键基因.在没有bicoid基因的昆虫中，otd基因取代了bicoid的部分功能，建立胚胎前后轴的极性.在昆虫原头体节形成过程中，otd等间隙基因直接激活体节极性基因的表达，而对控基因不起作用.此外，otd还与昆虫中枢神经和光感受器的形成有关.从进化方面来看，otd基因可能是从调控后生动物的光感受、脑发育和昼夜节律的基因中逐渐演变形成，并随着昆虫的系统发育而演化，其表达模式和功能既具有保守性又具有变异性.本文就昆虫otd基因的结构、功能和进化等方面的研究进展进行了综述.图1参62
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