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OALib Journal期刊
ISSN: 2333-9721
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立体定向放射外科治疗脑转移瘤预后因素分析
, PP. 1425-1428
Keywords: 脑转移瘤/放射疗法,立体定向放射外科,预后因素
Abstract:
目的评价立体定向放射外科(srs)治疗脑转移瘤的效果及预后因素。方法回顾性分析1994～2002年在巴黎tenon医院放疗科行srs(x线刀)治疗的脑转移患者102例,包括单发者78例,多发者24例,102例患者共有转移灶131个,转移灶最大直径≤4cm。其中18位患者同时接受全脑放疗(wbrt),93例患者120个转移灶有影像学随访。计算患者的生存期及局控率,并对潜在预后因素分别进行单因素和多因素分析。结果总体局控率和1年局控率分别为91.7%和85.3%,102例患者的中位生存期为11个月。单因素分析表明只有转移灶体积是影响局控率的预后因素;kps>70、年龄≤60、无颅外其他器官转移以及srs前行全脑照射是影响生存期的预后因素。多因素分析表明仅kps评分为生存独立预后因素。结论srs是脑转移的有效治疗方式,多种因素影响其预后。
| [1] | pirzkalla,debusj,lohrf,etal.radiosurgeryaloneorincombinationwithwhole-brainradiotherapyforbrainmetastases[j].jclinoncol,1998,16(11):3563-9.
|
| [2] | chidelma,suhjh,reddyca,etal.applicationofrecursivepartitionanalysisandevaluationoftheuseofwholebrainradiationamongpatientstreatedwithstereotacticradiosurgeryfornewlydiagnosedbrainmetastases[j].intjradiatoncolbiolphys,2000,47(4):993-9.
|
| [3] | borgeltb,gelberr,kramers,etal.thepalliationofbrainmetastases:finalresultsofthefirsttwostudiesbytheradiationtherapyoncologygroup[j].intjradiatoncolbiolphys,1980,6(1):1-9.
|
| [4] | hoffmanr,sneedpk,mcdermottmw,etal.radiosurgeryforbrainmetastasesfromprimarylungcarcinoma[j].cancerj,2001,7(2):121-31.
|
| [5] | hasegawat,kondziolkad,flickingerjc,etal.brainmetastasestreatedwithradiosurgeryalone:analternativetowholebrainradiotherapy[j]?neurosurgery,2003,52(6):1318-26.
|
| [6] | aoyamah,shiratoh,onimarur,etal.hypofractionatedstereotacticradiotherapyalonewithoutwhole-brainirradiationforpatientswithsolitaryandoligobrainmetastasisusingnon-invasivefixationoftheskull[j].intjradiatoncolbiolphys,2003,56(3):793-800.
|
| [7] | feuvretl,germaini,cornup,etal.firsttreatmentforbrainmetastasesbystereotacticradiosrugery[j].bullcancer,1999,86(7-8):666-72.
|
| [8] | shehatamk,youngb,reikb,etal.stereotaticradiosurgeryof468brainmetastases≤2cm:implicationsforsrsdoseandwholebrainradiationtherapy[j].intjradiatoncolbiolphys,2004,59(1):87-93.
|
| [9] | noelg,medionij,valeryca,etal.threeirradiationtreatmentoptionsincludingradiosurgeryforbrainmetastasesfromprimarylungcancer[j].lungcancer,2003,41(3):333-43.
|
| [10] | sneedpk,suhjh,goetschsj,etal.amulti-institutionalreviewofradiosurgeryalonevsradiosurgerywithwholebrainradiotherapyastheinitialmanagementofbrainmetastases[j].intjradiatoncolbiolphys,2002,53(3):519-26.
|
| [11] | beckerg,jeremicb,engelc,etal.radiosurgeryforbrainmetastases:thetuebingenexperience[j].radiotheroncol,2002,62(2):233-7.
|
| [12] | zabela,milker-zabels,thilmannc,etal.treatmentofbrainmetastasesinpatientswithnon-smallcelllungcancer(nsclc)bystereotacticlinac-basedradiosurgery:prognosticfactors[j].lungcancer,2002,37(1):87-94.
|
| [13] | sanghavisn,miranpuriss,chappellr,etal.radiosurgeryforpatientswithbrainmetastases:amulti-institutionalanalysis,stratifiedbythertogrecursivepartitioninganalysismethod[j].intjradiatoncolbiolphys,2001,51(2):426-34.
|
| [14] | weltmane,salvajolijv,brandtra,etal.radiosurgeryforbrainmetastases:ascoreindexforpredictingprognosis[j].jradiatoncolbiolphys,2000,46(5):1155-61.
|
| [15] | goyallk,suhjh,reddyca,etal.theroleofwholebrainradiotherapyandstereotacticradiosurgeryonbrainmetastasesfromrenalcellcarcinama[j].ihtjradiatoncolbiolphys,2000,47(4):1007-12.
|
| [16] | josephj,adlerjr,coxrs,etal.linearaccelerator-basessteteotaxicradiosurgeryforbrainmetastases:theinfluenceofnumberoflesionsonsurvival[j].jclinoncol,1996,14(4):1085-92.
|
| [17] | shawe,scottc,souhamil,etal.radiosurgeryforthetreatmentofpreviouslyirradiatedrecurrentprimarybraintumoursandbrainmetastases:initialreportofradiationtherapyoncologygroupprotocol90-05[j].intjradiatoncolbiolphys,1996,34(3):647-54.
|
| [18] | shawe,scottc,souhamil,etal.singledoseradiosurgicaltreatmentofrecurrentpreviouslyirradiatedprimarybraintumorsandbrainmetastases:finalreportofrtogprotocol90-05[j].intjradiatoncolbiolphys,2000,47(2):291-8.
|
| [19] | andrewsdw,scottcb,sperdutopw,etal.wholebrainradiationtherapywithorwithoutstereotacticradiosurgeryboostforpatientswithonetothreebrainmetastases:phaseⅲresultsofthertog9508randomisedtrial[j].lancet,2004,363(9422):1665-72.
|
| [20] | vesagasts,aguilarja,mercadoer,etal.gammakniferadiosurgeryandbrainmetastases:localcontrol,survival,andqualityoflife[j].jneurosurg,2002,97(5suppl):507-10.
|
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