OALib Journal期刊
ISSN: 2333-9721
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巨噬细胞移动抑制因子蛋白在胰腺癌组织表达的临床意义
, PP. 1301-1303
Keywords: 胰腺癌,巨噬细胞移动抑制因子,免疫组织化学
Abstract:
目的观察巨噬细胞移动抑制因子(mif)在胰腺癌组织中的表达及临床意义。方法应用免疫组织化学技术对36例胰腺癌组织中的mif蛋白表达进行研究。结果胰腺癌组织中的mif表达率为69.4%(25/36),高于正常胰腺组织表达率0(0/10)。统计学分析显示,mif蛋白表达与胰腺癌病理分级呈显著相关(p<0.01),与胰腺癌临床分期及有无局部淋巴结转移间无显著相关(p>0.05)。结论mif蛋白表达有可能与胰腺癌的发生有关。
References
[1] | 石玉生,徐素俊,郑小康,等.局部晚期胰腺癌三维适形放射治疗疗效观察[j].第一军医大学学报2004,24(2):213-5.shiys,xusj,zhengxk,etal.therapeuticeffectofthreedimensionalconformalradiotherapyonlocallyadvancedpancreaticcarcinoma[j].jfirstmilmeduniv/diyijunyidaxuexuebao,2004,24(2):213-5.
|
[2] | 周国雄,李兆申,许国铭,等.胰腺癌组织dpc4/smadmrna表达的临床意义[j].胰腺病学2002,2(1):25-7.zhougx,lizs,xugm,etal.theexpressionofdpc4/smadmrnainpancreaticcarcinoma[j].chinjpancreatol,2002,2(1):25-7.
|
[3] | kamimuraa,kamachim,nishihiraj,etal.intracellulardistributionofmacrophagemigrationinhibitoryfactorpredictstheprognosisofpatientswithadenocarcinomaofthelung[j].cancer,2000,89(2):334-41.
|
[4] | 邹衍泰,李朝龙.胆管结石合并胰腺癌两例报道[j].第一军医大学学报,1997,14,301.zhouyt,licl.twocasesreportonpancreatictumourcompanyedbygall-stone[j].jfirstmilmeduniv/diyijunyidaxuexuebao,1997,14,301.
|
[5] | shimizut,aber,nakamurah,etal.highexpressionofmacrophagemigrationinhibitoryfactorinhumanmelanomacellsanditsroleintumorcellgrowthandangiogenesis[j].biochembiophysrescommun,1999,264(3):751-8,
|
[6] | robertkleemann,angelikahausser,georggeiger,intracellularactionofthecytokinemiftomodulateap-1activityandthecellcyclethroughjabl[j].nature,2000,408(6809):211-6
|
[7] | katoy,nakatak,omagarik,etal.riskofhepatocellularcarcinomainpatientswithcirrhosisinjapan.analysisofinfectioushepatitisviruses[j].cancer,1994,74(8):2234-8.
|
[8] | roskamst,moshageh,vosrde,etal.heparansulfateproteoglycanexpressioninnormalhumanliver[j].hepatology,1995,21(4):950-8.
|
[9] | calandrat,bernhagenj,mitchellra,etal.themacrophageisanimportantandpreviouslyunrecognizedsourceofmacrophagemigrationinhibitoryfactor[j].jexpmed,1994,179:1895-1902.
|
[10] | bacherm,christinen,metzcn,etal.anessentialregulatoryroleformacrophagemigrationinhibitoryfactorint-cellactivationpnas[j].immunol,1995,154:3863-70.
|
[11] | takahashin,nishihiraj,satoy,etal.involvementofmacrophagemigrationinhibitoryfactorinthemechanismoftumorcellgrowth[j].molmed,1998,4:707-14.
|
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