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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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局部晚期胰腺癌三维适形放射治疗疗效观察
Keywords: 胰腺肿瘤,放射疗法,适形,治疗结果
Abstract:
目的评价两种适形放疗方法对局部晚期胰腺癌的疗效。方法67例局部晚期胰腺癌患者接受适形放射治疗,采用真空垫进行体位固定,增强ct扫描定位,三维治疗计划系统模拟治疗计划。患者随机分为a、b两组:a组单次放射剂量5~6gy,3次/周,总剂量45~54gy/8-12f/18~27d;b组单次放射剂量3gy,5次/周,总剂量45~54gy/15-18f/20~25d。结果放疗后1个月腹、背痛缓解总有效率95.9%,完全缓解率81.6%,a、b组分别为95.7%和69.2%;两组整体肿瘤退缩率为67.2%,a、b组分别为81.8%和51.6%;中位生存期12.5个月,a、b组患者2年生存率分别为35.3%和12.1%。结论低分割照射局部晚期胰腺癌,靶区单次剂量大对肿瘤杀伤作用强,而靶区周围正常组织剂量低,放射反应小,疗效肯定。
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