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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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线栓法大鼠缺血/再灌注脑损伤模型的改良
, PP. 1156-1159
Keywords: 缺血,线栓法,再灌注脑损伤,动物模型,大鼠
Abstract:
目的研究一种线栓法大鼠缺血/再灌注脑损伤模型的改良术式。方法结扎颈总动脉(cca),不结扎颈外动脉和翼腭动脉,用头皮针于cca结扎的远端穿刺导入3-0线栓造成缺血,通过拔出线栓形成再灌注。结果栓线长度(20.0±1.8)mm,造模成功率近70%,造模动物临床表现及病理表现典型。结论本术式简便,术者不需具备显微手术操作技巧,造模成功率较高。
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