|
OALib Journal期刊
ISSN: 2333-9721
费用：99美元
|
|
|
|
消化道肿瘤患者肠道通透性研究
, PP. 569-571
Keywords: 消化道肿瘤,肠粘膜屏障,肠道通透性,气相色谱,糖探针
Abstract:
目的测定晚期消化道肿瘤患者肠道通透性的改变,探讨消化道肿瘤是否影响肠粘膜屏障功能。方法健康志愿者、晚期消化道肿瘤患者各16名,每人口服乳果糖、甘露醇液后采集6h尿样。尿样和乳果糖、甘露醇的标准样经肟化处理后通过气相色谱分析仪进行检测分析。结果甘露醇峰、乳果糖峰出峰时间稳定,峰面积与含量呈线性相关;消化道晚期肿瘤患者与健康志愿者尿样中的乳果糖含量和乳果糖/甘露醇比值存在显著差异(p<0.05),乳果糖含量增高,而甘露醇含量2组无显著差异。结论晚期消化道肿瘤患者肠粘膜通透性增加,存在肠粘膜屏障功能障碍。
| [1] | swankgm,deitchea.roleofthegutinmultipleorganfailure:bacterialtranslocationandpermeabilitychanges[j].worldjsurg,1996,20(4):411-7.
|
| [2] | 谭建美,黄祥成.肠粘膜屏障损伤的机制[j].第一军医大学学报,2001,2l(8):627-9.tanjm,huangxc.mechanismsofgastrointestinaldysfunction[j].jfirstmilmeduniv/diyijunyidaxuexuebao,2001,21(8):627-9.
|
| [3] | aranowjs,finkmp.determinationofintestinalbarrierfailureincriticalillness[j].brjanaesth,1996,77(9):71-81.
|
| [4] | zieglertr,smithrj,o’dwyerst,etal.increasedintestinalpermeabilityassociatedwithinfectioninburnpatients[j].archsurg,1988,123(6):1313-9.
|
| [5] | traviss,menziesi.intestinalpermeability:functionalassessmentandsignificance[j].clinsci,1992,82(8):71-6.
|
| [6] | 吴承堂,黎沾良,熊德鑫,等.急性坏死性胰腺炎后肠道细菌与胰腺感染关系的研究[j].第一军医大学学报,1998,18(2):132-3.wuct,lizl,xiongdx,etal.experimentalstudyonintestinalbacterialtranslocationwithjm109bearingplasmidpuc18inacutenecrotizingpancreatitis[j].jfirstmilmeduniv/diyijunyidaxuexuebao,1998,18(2):132-3.
|
| [7] | 但汉雷,白杨,王继德,等.危重病人胃肠功能障碍与衰竭定量诊断评分方案[j].第一军医大学学报,2002,22(9):857.danhl,baiy,wangjd,etal.scoringprotocolforquantitativediagnosisofgastrointestinaldysfunctionandfailureinseverecases[j].jfirstmilmeduniv/diyijunyidaxuexuebao,2002,22(9):857.
|
| [8] | ronaldls,averyaj,williamg,etal.simultaneousdeterminationoflactuloseandmannitolinurineofburnpatientsbygas-liquidchromatography[j].clinchem,1992,38(3):343-5.
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|
