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OALib Journal期刊
ISSN: 2333-9721
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成肌调节因子myod与myogenin在肌肉损伤修复过程的动态变化
, PP. 542-545
Keywords: 成肌调节因子,myod,myogenin,肌肉再生
Abstract:
目的探讨成肌调节因子myod与myogenin在肌肉损伤修复过程中的动态表达。方法用盐酸布比卡因局部注射制作肌肉损伤模型,在损伤后不同时间点取腓肠肌行冰冻切片,he染色显示损伤肌肉的病理变化,用sabc法检测myod与myogenin的表达。结果myod在肌肉损伤后18h开始表达,48h达高峰;myogenin在肌肉损伤后24h开始表达,72h达高峰。结论myod与myogenin在肌肉损伤后的再生修复过程中起作用,可作为鉴定肌肉前体细胞和反映肌肉再生的指标。
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