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OALib Journal期刊
ISSN: 2333-9721
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微囊藻毒素lr对小鼠的急性毒性研究
Keywords: 微囊藻毒素,急性毒性,脏器系数
Abstract:
目的了解微囊藻毒素对小鼠的急性损伤作用.方法以balb/c小鼠为材料,腹腔注射μg./kg？b.w.和43μg/kg？b.w.剂量的微囊藻毒素lr,测定脏器系数和一系列生化指标.结果肾脏指数与肝脏指数明显增加,表明两种器官都受到损伤;血清中天冬氨酸转氨和丙氨酸转氨酶活力上升,尿素含量下降预示着肝脏损伤,尿酸含量上升则预示肾脏损伤的发生.结论肾脏也可能是易受微囊藻毒素损伤的器官.
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