OALib Journal期刊
ISSN: 2333-9721
费用:99美元
|
|
|
常通口服液预防术后肠粘连的实验研究
Keywords: 肠疾病,粘连,手术后并发症,常通口服液
Abstract:
目的观察中药常通口服液用于术后腹腔肠粘连的效果。方法选取54只sd雄性大鼠随机分为6组(n=9):正常对照组、模型对照组、四磨汤组、常通口服液低、中、高剂量组。除正常对照组外,其余大鼠均按ellis法制备成肠粘连模型。正常及模型对照组予以蒸馏水灌胃(10ml/kg);四磨汤组以10ml/kg灌胃给药;常通口服液低、中、高剂量组分别按4.3、8.6、17.2g/kg灌胃给药。各组于术后第7天取血,测定白细胞(wbc)计数及纤维蛋白原(fib)浓度;同时进行粘连程度肉眼分级。结果常通口服液能明显减轻肠粘连程度,降低大鼠血浆中wbc计数及fib浓度。结论常通口服液能够预防腹腔术后肠粘连形成。
References
[1] | hemadeho,chilukuris,bonetv,etal.preventionofperitonealadhesionsbyadministrationofsodiumcarboxymethylcelluloseandoralvitamine[j].surgery,1993,114(5):907-10.
|
[2] | 王春兴,王哲.腹膜粘连的病因、病理、预防及治疗[j].河北医药(hebeimedpharmj),1989,11(2):103-4.
|
[3] | ellish.theetiologyofpostoperativeabdominaladhesion:anexperimentalstudy[j].brjsurg,1962,50(1):10-6.
|
[4] | nairsk,bhalzk,auroraal.roleofproteolyticenzymesinthepreventionofpost-operativeintra-peritonealadhesions[j].archsurg,1974,108:849-55.
|
[5] | monkbj,bermanml,montzfj.adhesionsafterextensivegynecologicsurgeryclinicalsignificance,etiology,andprevention[j].amjobstetgynecol,1994,170(5pt1):1396-408.
|
[6] | 蔡华芳,刘学莉,钱伯初,等.桃蛭枳朴冲剂对大鼠实验性肠粘连的预防作用及其治疗机理的研究[j].中国中西医结合杂志,1997,17(10):603-6.caihf,liuxl,qianbc,etal.effectoftaozhizhipugranuleonintestinaladhesioninratsandexplorationofitstherapeuticmechanism[j].chinjintegrtraditwestmed,1997,17(10):603-6.
|
[7] | 王荣泉,陈菊珍,任光源,等.腹腔内注入复方丹参液加大承气汤治疗粘连性肠梗阻临床观察[j].中国中西医结合杂志,1994,14(10):595-7wangrq,chenjz,rengy,etal.intraperitonealperfusionofcompoundinjectionofsalviaailtiorrhizawithdachengqidecoctionintreatingadhesiveintestinalobstruction[j].chinjintegrtraditwestmed,1994,14(10):595-7.
|
[8] | 杨士友,黄世福,孙备,等.大鼠创伤性肠粘连模型的制备及黄厚排气颗粒对其粘连程度的影响[j].上海实验动物科学,2002,22(3):1414.yangsy,huangsf,sunb,etal.preparationoftraumaticintestinaladhesionmodelofratsandtheeffectofhuanghoupaiqigranuleonthedegreeofintestinaladhesion[j].shanghailabanimsci,2002,22(3):141-4.
|
[9] | 杨方修,金正根,许文胜.大承气汤和大黄对豚鼠结肠平滑肌细胞电活动的影响[j].中国中西医结合杂志,1993,13(1):33-4.yangfx,jinzg,xuws.effectsofdachengqidecoctionandrhubarboncelluarelectricalactivitiesinsmoothmuscleofguinea-pig’staeniacoil[j].chinjintegrtraditwestmed,1993,13(1):33-4.
|
[10] | 陈福春,陈国富,林决明."金黄平安汤"治疗肠粘连的临床疗效观察[j].中西医结合实用临床急救,1998,5(10):452-4.chenfc,chengf,linjm.observationontherapeuticefficacyofjinhuangpingandecoctiononintestinaladhesion[j].integrtraditchinwestmedpractcritcaremed,1998,5(10):452-4.
|
[11] | 李春越.血瘀症及活血化瘀药的研究进展[j].中西医结合杂志(jintegrtraditwestmed),1988,8(5):317-22.
|
[12] | 刘敏,彭明辉,刘铭,等.胰岛素及丹参对体外成纤维细胞的影响的实验研究[j].中国修复重建外科杂志,1998,12(1):524.lium,pengmh,lium,etal.theexperimentalstudyoftheeffectofinsulinanddanshenoncultureoffibroblastinvitro[j].chinjreparatreconstrsury,1998,12(1):52-4.
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|