|
OALib Journal期刊
ISSN: 2333-9721
费用：99美元
|
|
|
|
pet/ct图像融合对骨转移瘤放射治疗肿瘤区勾画的影响
Keywords: 体层摄影术,发射型计算机,体层摄影术,x线计算机,肿瘤区体积,图像处理,计算机辅助,骨转移瘤
Abstract:
目的评价pet/ct图像融合在三维适形放射治疗骨转移瘤肿瘤靶区勾画中的作用。方法选取3例病理证实原发灶为肺癌、肝癌和肾癌且合并全身多发性骨转移瘤患者,选择腰椎、胸椎、肋骨、髂骨、肩胛骨、股骨转移病灶各1处,标记为bm1~6,由8位放射肿瘤学医师分别在治疗计划ct上勾画6处骨转移瘤的肿瘤区体积(gtv),比较依据ct和pet/ct图像融合资料勾画gtv的差异。结果有骨皮质破坏的病灶bm1~5,依据ct勾画的gtv较依据pet/ct勾画的gtv大(p<0.05),而无明显骨皮质破坏的病灶bm6则相反(p<0.05)。依据pet/ct勾画gtv时,不同观察者之间的差异小于依据ct勾画gtv时的差异。结论pet/ct图像融合能提高骨转移瘤gtv勾画的精确性和重复性,从而减少对周围正常组织损伤而增加放射治疗的增益比。
| [1] | 殷蔚伯,谷铣之.肿瘤放射治疗学[m].第3版,北京:中国协和医科大学出版社,2002.1088.
|
| [2] | 胡永成.全国骨转移瘤治疗专题座谈会会议纪要[j].中华骨科杂志(chinjorthop),2003,23(6):323-5.
|
| [3] | caldwellcb,mahk,ungyc,etal.observervariationincontouringgrosstumorvolumeinpatientswithpoorlydefinednon-smallcelllungtumorsonct:theimpactof18fdg-hybridpetfusion[j].intjradiatoncolbiolphys,2001,51(4):923-31.
|
| [4] | ungyc,caldwellcb,mahk,etal.fusingflourodeoxyglucose(fdg)-hybridpettoctimagessignificantlyalterstreatmentplanningintheradicaltreatmentofnon-smallcellcarcinomaofthelung[j],intjradiatoncolbiolphys,2000,48(3):327-8.
|
| [5] | 卢光明,陈君坤.ct诊断与鉴别诊断[m].南京:东南大学出版社,1999.521.
|
| [6] | 范国华,龚建平,钱铭辉.脊柱骨转移瘤的ct诊断[j].放射学实践(radiolpractice),2002,17(6):503-4.
|
| [7] | 申文江.骨转移瘤[j].中华放射肿瘤学杂志(chinjradiatoncol),1994,3(1):62-5.
|
| [8] | 卜俊国,袁亚维,陈新杰.局部野放射治疗骨转移瘤的经验分析[j].第一军医大学学报,2000,20(3):281-2.bujg,yuanyw,chenxj.theexperienceandanalysisoflocalfieldradiationtherapyofbonemetastases[j].jfirstmilmeduniv/diyijunyidaxuexuebao,2000,20(3):281-2.
|
| [9] | linstadtde.spinalcord[a],in:textbookofradiationoncology[m].philadelphia:w.b.saunderscompany,1998.401-12.
|
| [10] | bradleyjd,leumwananonthachain,pmdyja,etal.grosstumorvolume,criticalprognosticfactorinpatientstreatedwiththreedimensionalconformalradiationtherapyfornon-smallcelllungcarcinoma[j].intjradiatoncolbiolphys,2002,52(1):49-57.
|
| [11] | loguejp,sharrockcl,cowanra,etal.clinicalvariabilityoftargetvolumedescriptioninconformalradiotherapyplanning[j].intjradiatoncolbiolphys,1998,41(4):929-31.
|
| [12] | steenejv,linthoutn,meyj,etal.definitionofgrosstumorvolumeinlungcancer:interobservervariability[j].radiotheroncol,2002,62(1):37-49.
|
| [13] | giraudp,elless,helfres,etal.conformalradiotherapyforlungcancer:differentdelineationofthegrosstumorvolume(gtv)byradiologistsandradiationoncologists[j].radiotheroncol,2002,62(1):27-36.
|
| [14] | 仇道斌,刘丽娟,孙爱君,等.ct相对于18f-fdgpet对脊椎转移瘤的诊断评价[j].中国医学影像技术,2000,16(7):550-2.qiudb,liulj,sunaj,etal.comparisonofctand18f-fdgpetindetectingspinalmetastases[j].chinajmit,2000,16(7):550-2.
|
| [15] | nestleu,walterk,schmidts,etal.18f-deoxyglucosepositronemissiontomography(fdg-pet)fortheplanningofradiotherapyinlungcancer:highimpactinpatientswithatelectasis2[j].intjradiatoncolbiolphys,1999,44(3):593-7.
|
| [16] | jangs,greskovichjf,millaba,etal.effectsofpet/ctimageregistrationonradiationtreatmentplanninginlungcancer[j].intjradiatoncolbiolphys,2003,57(2):s414-5.
|
| [17] | even-sapire,metseru,flusserg,etal.assessmentofmalignantskeletaldisease:initialexperiencewith(18)f-fluoridepet/ctandcomparisonbetween(18)f-fluoridepetand(18)f-fluoridepet/ct[j].jnuclmea,2004,45(2):279-84.
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|
