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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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聚谷氨酸及其衍生物在新型药物传输系统中的应用
DOI: 10.3969/j.issn.1671-7627.2003.02.017, PP. 75-78
Keywords: 聚谷氨酸,药物传输系统,控释/缓释,靶向
Abstract:
聚谷氨酸是生物可降解的高分子材料,作为新型药物载体具有广泛的用途.综述了聚谷氨酸及其衍生物在改善药物的水溶性、降低毒性、控制药物释放以及提高药物靶向性等方面的研究,为药物新剂型的开发提供参考.
| [1] | ogaway,yamaguchif,yuasak.efficientproductionofgamma-polyglutamicacidbybacillussubtilis(natto)injarfermenters[j].bioscience,biotechnology,andbiochemistry,1997,(10):1684-1687.doi:10.1271/bbb.61.1684.
|
| [2] | mitras,vandressm.pro-drugcontrolledreleasefrompolyglutamicacid[j].polymericpreprints(americanchemicalsocietydivisionofpolymerchemistry),1979(2):32-35.
|
| [3] | hostek,schachte,seymourl.newderivativesofpolyglutamicacidasdrugcarriersystems[j].journalofcontrolledrelease,2000.53-61.
|
| [4] | pmarkland,gordonl.modifiedpolypeptidescontainingγ-benzylglutamicacidasdrugdeliveryplatforms[j].internationaljournalofpharmaceutics,1999(3):183-192.doi:10.1016/s0378-5173(98)00373-1.
|
| [5] | 潘仕荣,黄宁芳,林在峰.聚-γ-苄酯-l-谷氨酸酯合成的改进[j].生物医学工程学杂志,1990(4):321-324.
|
| [6] | 潘仕荣,易武,施峰.18-甲基炔诺酮-聚氨基酸微球的制备与体外释药实验[j].中国药学杂志,1993(7):405-408.
|
| [7] | 李崇辉,温守明,池木根.肝靶向配体半乳糖基白蛋白和多pga[j].生物化学与生物物理进展,1998(6):532-535.
|
| [8] | perezcamerog,congregadof,bouj.biosynthesisandultrasonicdegradationofbacterialpoly(γ-glutamicacid)[j].journalofbiotechnolbioeng,1999(1):110-115.doi:10.1002/(sici)1097-0290(19990405)63:1<110::aid-bit11>3.0.co;2-t.
|
| [9] | sandafumio,fujiyamataizo,endotakeshi.chemicalsynthesisofpoly-gamma-glutamicacidbypolycondensationofgamma-glutamicaciddimmer:synthesisandreactionofpoly-gamma-glutamicacidmethyester[j].journalofpolymerscienceparta:polymerchemistry,2001(5):732-741.doi:10.1002/1099-0518(20010301)39:5<732::aid-pola1045>3.0.co;2-p.
|
| [10] | 原敏夫,上田诚之助.pga生产的基因解析[j].发酵与工业(日本),1985,(10):910-918.
|
| [11] | hidetoshik,toshiom,kazumichiu.productionofpoly(γ-glutamicacid)bybacillussubtilisf-2-01[j].bioscience,biotechnology,andbiochemistry,1993(7):1212-1213.
|
| [12] | 潘仕荣,施锋,黄宁芳.α-氨基酸共聚物的生物降解性[j].中国生物医学工程学报,1993(3):161-167.
|
| [13] | 吴晓明,何彦萍,李松.水溶性三尖杉磷碱聚氨基酸酯或其盐含它们的药物组合及其医药用途[p].cn1288010a,2001.
|
| [14] | 吴晓明.聚谷氨酸或聚谷氨酸钠紫杉云宁a酯化合物及其用途[p].cn:1243125a,2000.
|
| [15] | lic,wallaces.watersolublepaclitaxelderivatives[p].wo:9949901,1999.
|
| [16] | lic,kes.tumorirradiationenhancesthetumor-specificdistributionofpoly(l-glutamicacid)-conjugationpaclitaxelanditsantitumorefficacy[j].clinicalcancerresearch,2000(7):2829-2834.
|
| [17] | oldhamea,lic,kes.comparisonofactionofpaclitaxelandpoly(l-glutamicacid)paclitaxelconjugateinhumanbreastcancercells[j].internationaljournalofoncology,2000(1):125-132.
|
| [18] | bhattr,devriesp.polyglutamicacid-camptothecinsconjugatesandmethodsofpreparation[p].us:2002016285a1,2002.
|
| [19] | singerjw,devriesp,bhattr.conjugationofcamptothecinstopoly-(l-glutamicacid)[j].annalsofthenewyorkacademyofsciences,2000.136-150.doi:10.1111/j.1749-6632.2000.tb07032.x.
|
| [20] | 徐凤华,蒋雪涛,主皓.均匀设计优化聚谷氨酸与表阿霉素的交联条件[j].中国医院药学杂志,1998(5):214-215.doi:10.3321/j.issn:1001-5213.1998.05.013.
|
| [21] | 徐凤华,蒋雪涛,主皓.聚谷氨酸-表阿霉素偶合物的稳定性研究[j].解放军药学学报,1999(6):37-40.doi:10.3969/j.issn.1008-9926.1999.06.014.
|
| [22] | avichezerd,schechterb.functionalpolymersindrugdelivery:carrier-supportcddp(cis-platin)complexsofpolycar-boxylates-effectonhumanovariancarcinoma[j].reactiveandfunctionalpolymers,1998(1):59-69.
|
| [23] | zuponma,fangsm,christensenjm.invivoreleaseofnorethiodronecoupledtoabiodegradablepoly(α-aminoacid)drugdeliverysystem[j].journalofpharmaceuticalsciences,1983,(11):1323-1327.doi:10.1002/jps.2600721121.
|
| [24] | 冯敏,潘仕荣,吴伟荣.聚α-氨基酸黄体酮微球的制备及释药研究[j].中国药科大学学报,2001(4):253-256.doi:10.3321/j.issn:1000-5048.2001.04.004.
|
| [25] | akamatsuk,imaim,yamasakiy.dispositioncharacteristicsofglycosylatedpoly(aminoacid)aslivercell-specificdrugcarrier[j].journalofdrugtargeting,1998(3):229-239.doi:10.3109/10611869808997897.
|
| [26] | hidekih,makiyan,yoshinobut.developmentandpharmacokineticsofgalactosylatedpoly-l-glutamicacidasabiodegradablecarrierforliverspecificdrugdelivery[j].pharmaceuticalresearch,1996(6):880-884.
|
| [27] | 徐凤华,蒋雪涛.单克隆抗体-表阿霉素免疫偶合物的制备和体外活性[j].药学学报,1996(8):632-636.
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