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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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4种11脱氧甘草次酸3,30双糖链皂苷的合成
, PP. 130-134
Keywords: 11脱氧甘草次酸,皂苷,糖苷键,合成
Abstract:
合成4种11脱氧甘草次酸3,30双糖链皂苷。以苯甲酰基保护的糖基三氯乙酰亚胺酯为供体，在tmsotf的催化作用下与11脱氧甘草次酸c3位羟基和c30位羧基进行偶联，以较好的收率制备得11脱氧甘草次酸3,30双糖链皂苷（6a，6b，6c，6d）。化合物均未见报道，结构经核磁共振（1hnmr）确证，均为1,2反式构型糖苷键。
| [1] | 刘明国,付莎莉.糖苷化合物功能简介[j].湖北三峡学院学报,2000,22(2):50-54.
|
| [2] | hedm,kaleemi,qinsy,etal.biosynthesisofglycyrrheticacid3-o-mono-β-d-glucuronidecatalyzedbyβ-d-glucuronidasewithenhancedbondselectivityinanionicliquid/bufferbiphasicsystem[j].processbiochemistry,2010,45:1916-1922.
|
| [3] | saitos,sasakiy,kurodak,etal.preparationofglycyrrheticacidbeta-glycosideshavingbeta(1(2)-linkeddisaccharidesbytheuseof2-o-trichloroacetyl-beta-d-pyranosylchloridesandtheircytoprotectiveeffectsonhepaticinjuryinvivo[j].chemical&pharmaceuticalbulletin,1993,41(3):539-543.
|
| [4] | saitos,ebashij,sumitas,etal.comparisonofcytoprotectiveeffectsofsaponinsisolatedfromleavesofaraliaelataseem.(araliaceae)withsynthesizedbisdesmosidesofoleanoicacidandhederageninoncarbontetrachloride-inducedhepaticinjury[j].chemical&pharmaceuticalbulletin,1993,41(8):1395-1401.
|
| [5] | yoshikawam,haradae,matsudah,etal.elatosidesaandb,potentinhibitorsofethanolabsorptioninratsfromthebarkofaraliaelataseem:thestructure-activityrelationshipsofoleanolicacidoligoglycosides[j].chemical/pharmaceuticalbulletin,1993,41(11):2069-2071.
|
| [6] | yoshikawam,haradae,murakamit,etal.escins-ia,ib,iia,iib,andiiia,bioactivetriterpeneoligoglycosidesfromtheseedsofaesculushippocastanuml:theirinhibitoryeffectsonethanolabsorptionandhypoglycemicactivityonglucosetolerancetest[j].chemical/pharmaceuticalbulletin,1994,42(6):1357-1359.
|
| [7] | yub,xiej,dengs,etal.firstsynthesisofabidesmosidictriterpenesaponinbyahighlyefficientprocedure[j].jamcemsoc,1999,121:12196-12197.
|
| [8] | yanmc,liuy,luwx,etal.facilesynthesisandcytotoxicityoftriterpenoidsaponinsbearingauniquedisaccharidemoiety:hederacolchisidea1anditsanalogues[j].carbohydrateresearch,2008,343:780-784.
|
| [9] | 周艳萌,吴忠明,向晓波.土贝母皂苷体外抗乙型肝炎病毒的药效研究[j].时珍国医国药,2006,17(11):2134-2136.
|
| [10] | wangyl,chend,wujl.effectsandmechanismoftotalsaponinsofpanaxnotoginsengonanti-inflammationandanalgesia[j].cjim,1996,2(2):86-90.
|
| [11] | 王晶,刘春明,白鹤龙,等.中药中皂苷类化合物的抗氧化活性评价研究[j].时珍国医国药,2010,21(6):1485-1487.
|
| [12] | srivastavasp,mishraa,bhatiav,etal.acaciacatechuhardwood:potentialanti-diabeticcumanti-dyslipidemic[j].medchemres,2010，20（9）：1732-1739.
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