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植物中mir160/mir167/mir390家族及其靶基因研究进展

DOI: 10.3969/j.issn.1000-2006.2014.03.030, PP. 155-159

Keywords: microrna,靶基因,沉默复合体,植物生长发育

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Abstract:

microrna(mirna)是真核生物中广泛存在的一类长21~23个核苷酸的非编码rna分子,通过与靶基因mrna的特异结合调节基因转录后表达,在调控细胞周期、生物体发育时序等方面起重要作用。mir160、mir167和mir3903个mirnas家族均为靶向arf(auxinresponsefactor)基因家族,预示着它们在行使调控功能的过程中既有相似性又有特异性。笔者详细阐述了mir160/mir167/mir390在植物发育过程中的调控作用及与其靶基因之间的相互调控关系,发现mir160/mir167/mir390均在植物生长发育过程中发挥重要的作用,但mir160则侧重于调控胚胎和根的发育,mir167侧重于调控植物花和果实的发育,而mir390则对植物横向器官的发育具有调控作用,并且,mir160/mir167/mir390与其靶基因之间存在反馈调节作用。

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