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OALib Journal期刊
ISSN: 2333-9721
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毛杨梅树皮原花色素对小鼠急性毒性及抗氧化性的影响
DOI: 10.3969/j.issn.1000-2006.2013.04.016, PP. 85-89
Keywords: 毛杨梅树皮,原花色素,急性毒性,抗氧化性
Abstract:
探讨了毛杨梅树皮原花色素提取物的安全性,分析了毛杨梅树皮原花色素对小鼠的急性毒性以及在小鼠体内的抗氧化性能。结果表明:毛杨梅树皮原花色素提取物经口的ld50为5g/kg。毛杨梅树皮原花色素给药后,小鼠血清内的过氧化氢酶(cat)、超氧化物歧化酶(sod)活性显著性增加(p<0.05),丙二醛(mda)含量减少。小鼠肝内的cat活力显著增加,mda含量也有所增加,但是并没有显著性差异(p>0.05)。因此,毛杨梅树皮原花色素属于实际无毒物质,毛杨梅树皮原花色素提取物对小鼠机体具有一定的抗氧化作用。
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