|
OALib Journal期刊
ISSN: 2333-9721
费用：99美元
|
|
|
|
α-蒎烯合成樟脑醌的研究
DOI: 10.3969/j.issn.1000-2006.2013.03.022, PP. 123-128
Keywords: α-蒎烯,2-氯莰烷,冰片烯,樟脑醌
Abstract:
以α-蒎烯为原料,与hcl加成、异构得到2-氯莰烷,再经消除反应得到冰片烯,以丙酮-水混合溶剂为反应介质,高锰酸钾为氧化剂氧化冰片烯,得到樟脑醌。探讨了相转移催化剂及溶剂种类、kmno4用量、丙酮与水的体积比,以及溶剂用量、反应温度、反应时间等对冰片烯氧化反应的影响,确定了适宜的氧化工艺条件:以高锰酸钾为氧化剂,高锰酸钾与冰片烯的物质量之比为3.0:1;以丙酮-水混合溶剂作为氧化反应介质,丙酮与水的体积比为3:1,丙酮-水混合溶剂与冰片烯的体积质量比为20:1(ml/g);反应温度为30℃;反应时间4h。在此工艺条件下,樟脑醌得率达85%以上。采用gc-ms、ftir、1hnmr、13cnmr等分析手段对合成所得产物的化学结构进行了分析测定。
| [1] | lawrencejr,oneillft,sheridanjt.photopolymerholographicrecordingmaterial[j].optik-internationaljournalforlightandelectronoptics,2001,112(10):449-463.
|
| [2] | jakubiakj,allonasx,fouassierjp,etal.camphorquinoneaminesphotoinitatingsystemsfortheinitiationoffreeradicalpolymerization[j].polymer,2003,44:5219-5226.
|
| [3] | schwabfc.photoinitiatorsaslightsensitivedegradantsforpolyethylene:us,4983645[p].1991-01-08.
|
| [4] | belseys,dankstn,wagnerg.microwave-assistedseleniumdioxideoxidationofcamphorderivativestodicarbonylcompoundsandoxoimines[j].syntheticcommunications,2006,36:1019-1024.
|
| [5] | hattorik,yoshidat,rikutak,etal.anewoxidationof3-bromocamphortocamphorquinone[j].chemlett,1994,10:1885-1888.
|
| [6] | 张浩波,王明亮.樟脑醌的合成[j].江苏化工,2005,33(5):35-36.zhanghb,wangml.synthesisofcamphorquinone[j].jiangsuchemicalindustry,2005,33(5):35-36.
|
| [7] | longjh.ontheopticalrotationofpennehydrochloride[j].jchemsoc,1989,21(8):637-642.
|
| [8] | trukhina,kruchkovf,hansenlk,etal.toxaphenechemistry:separationandcharacterisationofselectedenantiomersofthepolychloropinenemixtures[j].chemosphere,2007,67(9):1695-1700.
|
| [9] | marsaioliaj,nurnbergv,sarragiottomh.envisaginganoldreactionfromanewpointofview[j].jorgchem,1989,54:5838-5839.
|
| [10] | 张淑娴,利允隆.樟脑醌合成的研究进展[j].广州化学,1998(2):47-50.zhangsx,liyl.developmentofsynthesisofcamphorquinone[j].guangzhouchemistry,1998(2):47-50.
|
| [11] | andrzejewskae,lindénla,rabekjf.theroleofoxygenincamphorquinone-initiatedphotopolymerizationl[j].macromochemcommun,1998,119:441-449.
|
| [12] | cookwd.photopolymerizationkineticsofdimethacrylatesusingthecamphorquinone/amineinitiatorsystem[j].polymer,1992,33:600-609.
|
| [13] | meinwaldj,klingeleho.photochemicalreactionsofcamphorquinone[j].jamchemsoc,1966,88:2071-2073.
|
| [14] | husárb,lukáci.photooxidationofcamphorquinoneinpolystyrenematrix[j].journalofphotochemistryandphotobiologya:chemistry,2011,223:189-193.
|
| [15] | schneiderlfj,cavalcantelm,prahlsa,etal.curingefficiencyofdentalresincompositesformulatedwithcamphorquinoneortrimethylbenzoyl-diphenyl-phosphineoxide[j].dentalmaterials,2012,28:392-397.
|
| [16] | groselju,medena,stanovnikb,etal.synthesisofspiro[bicyclo
|
| [17] | [2.2.heptane-2,20-furan]-3-aminesviastereoselectivecycloadditionsoftrimethylenemethaneto(1s,3ez,4r)-3-arylimino-1,7,7-trimethylbicyclo
|
| [18] | [2.2.heptan-2-ones[j].tetrahedron:asymmetry,2007,18:2365-2376.
|
| [19] | euismk.attemptedkineticresolutionof1,2-diolsbycamphorquinone:aenerationof(r)-(chloromethyl)oxirame[j].jchemsocperkintransi,1991,4:747-755.
|
| [20] | 都恒青,赵曦,方洪钜.木香薷挥发油成分的研究[j].药物分析杂志,1989,9(1):18-21.duhq,zhaoy,fanghj.studiesonthecomponentofessentialoilsofeisholtziastauntoniibenth[j].chinesejournalofpharmaceuticalanalysis,1989,9(1):18-21.
|
| [21] | evanwc,ridgionjm,simonsenjl.preparationofcamphorquinone[j].jchemsoc,1934(0):137-138.
|
| [22] | 程健,冯涛,李开婧,等.冰片烯的合成研究[j].林产化学与工业,2009,29(2):54-58.chengj,fengtao,likj,etal.studyonthesynthesisofbornylene[j].chemistryandindustryofforestproducts,2009,29(2):54-58.
|
| [23] | roberth,shapirodjh.2-bornene[j].organicsynthesescoll,1988(6):172.
|
| [24] | 臧运晓,哈成勇,沈丹丹,等.α-蒎烯合成2-羟基-3-蒎酮的研究[j].林产化学与工业,2009,29(3):69-72.zangyx,hacy,shendd,etal.studyonsynthesisof2-hydroxy-3-pinanonefromα-pinene[j].chemistryandindustryofforestproducts,2009,29(3):69-72.
|
| [25] | 陆国元.有机反应与有机合成[m].北京:科学出版社,2009.
|
Full-Text
|
|
Contact Us
service@oalib.com QQ:3279437679 
WhatsApp +8615387084133
|
|
