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药学学报  2013 

透明质酸肿瘤靶向给药系统的研究进展

, PP. 1376-1382

Keywords: 透明质酸,药物载体,肿瘤靶向

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Abstract:

透明质酸(hyaluronicacid,ha)作为抗癌药物传递载体应用于肿瘤治疗领域,已成为肿瘤靶向给药系统研究的热点。ha本身具有识别肿瘤细胞表面过度表达的特定受体的能力,可以将抗癌药物靶向传递到肿瘤细胞内,从而更好地杀死肿瘤细胞。本文主要介绍了ha的基本特性和肿瘤靶向的生理学基础,同时,重点综述了近年来基于不同形式的ha肿瘤靶向给药系统的研究进展。

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