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药学学报  2015 

m3受体作为防治心血管疾病新靶点的研究进展

, PP. 393-399

Keywords: m3受体,心血管疾病,药物靶点,转基因,信号分子

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Abstract:

心血管疾病因其具有高发病率和死亡率的特点,严重威胁着人类的健康.人们一直在致力于对心血管疾病的研究,期望可以找到更有效的治疗方法.在心脏上发现存在功能性毒蕈碱型乙酰胆碱受体(muscarinicacetylcholinereceptor,machr,m受体)中的m3受体后,m3受体便成为了研究心血管疾病的新领域.而随着研究的深入进行,人们发现m3受体对多种心血管疾病具有保护作用,这也使m3受体有望成为治疗心血管疾病的新靶点.本综述围绕m3受体,主要从其在心脏上的功能、对心血管疾病的影响以及其机制等方面进行阐述,期望能对今后m3受体相关疾病的研究起到支持、借鉴和鼓励作用.

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