OALib Journal期刊
ISSN: 2333-9721
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川桑的化学成分及其细胞毒作用
, PP. 579-582
Keywords: 川桑,黄酮,川桑素,细胞毒作用
Abstract:
从川桑树枝的95%乙醇提取物中分离得到1个新的黄酮类化合物,命名为notabilisink(1),4个已知黄酮类化合物,分别为morusin(2)、mulberrofurana(3)、neocyclomorusin(4)和mornigrolf(5),化合物2~5均为首次从该植物中分离出来。notabilisini和notabilisinj对hct-116、hepg2、a2780细胞有一定的杀伤作用,ic50为1.47~5.46μmol·l-1;morusin对5种人肿瘤细胞(bgc823、a2780、hct-116、hepg2和nci-h1650)都有较强的杀伤作用,ic50为0.74~1.58μmol·l-1。
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