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OALib Journal期刊
ISSN: 2333-9721
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金属特性碳纳米管的筛选分离及对人类乳腺癌细胞的光热效应
, PP. 980-985
Keywords: 碳纳米管,mcf-7细胞,光热效应
Abstract:
分离并研究金属碳纳米管(m-swnts)的光热效应及其对乳腺癌细胞的抑制作用。采用pmpv(poly[(m-phenylenevinylene)-alt-(p-phenylenevinylene)])从单壁碳纳米管(swnts)中分离得到具有金属特性碳纳米管,测定其光热效应,与mcf-7乳腺癌细胞共同培养,在808nm波长下,用红外光(nir)以2w·cm-2的强度照射细胞3min,mtt比色法测定m-swnts对mcf-7细胞的杀灭作用;流式细胞术测定m-swnts对mcf-7细胞凋亡的影响。结果表明,用pmpv可有效分离m-swnts,其光热效应明显增强;可以抑制mcf-7细胞的存活率,促进mcf-7细胞凋亡,其效果强于未经分离的swnts。通过pmpv分离的m-swnts具有更高的光热转化效率,并且对mcf-7细胞具有更强的杀灭效果。
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