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OALib Journal期刊
ISSN: 2333-9721
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小叶臭黄皮中12个苯环衍生物
, PP. 1689-1693
Keywords: 小叶臭黄皮,苯乙醇,苯环衍生物
Abstract:
对小叶臭黄皮(clausenaexcavata)根、茎和叶部位进行了化学成分研究,经过一系列正相和反相色谱柱和高效液相色谱等现代分离技术,分离得到12个苯环衍生物(1～12),并通过ms、nmr、ir等波谱学方法对这些化合物进行结构鉴定,其中(2'r)-4-(2',3'-dihydroxy-3'-methyl-butanoxy)-phenethanol(1)为一个新化合物,化合物3和4为两个新天然产物,化合物5～8、10～12均为首次从该植物中分离得到.测定了化合物1对a549、hela和bgc-823的细胞毒活性及其对candidaalbicans、staphylococcusaureus的抑菌活性,结果显示化合物1没有细胞毒和抑菌活性.
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