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OALib Journal期刊
ISSN: 2333-9721
费用：99美元
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碳酸酐酶ix小分子抑制剂的研究进展
, PP. 1637-1643
Keywords: 碳酸酐酶ix,抑制剂,缺氧,抗肿瘤
Abstract:
碳酸酐酶ix(caix)是一个肿瘤相关蛋白,由于其在多种肿瘤组织中高度表达而在正常组织中几乎不表达,近年来成为一个潜在的抗癌靶点。寻找能够选择性抑制caix的小分子抑制剂将成为未来的焦点。本文对其在肿瘤生理活动中的作用、三维晶体结构的特征及小分子抑制剂研究进展进行综述。
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