Kawasaki H, Mizuseki K, Nishikawa S, et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity[J]. Neuron, 2000, 28(1):31-40.
[2]
Okabe S, Forsberq-Nilsson K, Spiro AC, et al. Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro[J]. Mech Dev, 1996, 59:89-102.
[3]
Cohen CB. Ethical and policy issues surrounding the donation of cryopreserved and fresh embryos for human embryonic stem cell research[J]. Stem Cell Rev, 2009, 5(2):116-122.
[4]
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors[J]. Cell, 2007, 131(5):861-872.
[5]
Urbach A, Bar-Nur O, Daley GQ, et al. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells[J]. Cell Stem Cell, 2010, 6(5):407-411.
[6]
Caiazzo M, Dell''Anno MT, Dvoretskova E, et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts[J]. Nature, 2011, 476:224-227.
[7]
Vierbuchen T, Ostermeier A, Pang ZP, et al. Direct conversion of fibroblasts to functional neurons by defined factors[J]. Nature, 2010, 463:1035-1041.
[8]
Marro S, Pang ZP, Yang N, et al. Direct lineage conversion of terminally differentiated hepatocytes to functional neurons[J]. Cell Stem Cell, 2011, 9:374-382.
[9]
Pang ZP, Yang N, Vierbuchen T, et al. Induction of human neuronal cells by defined transcription factors[J]. Nature, 2011, 476:220-223.
[10]
Son EY, Ichida JK, Wainger BJ, et al. Conversion of mouse and human fibroblasts into functional spinal motor neurons[J]. Cell Stem Cell, 2011, 9:205-218.
[11]
Maisel M, Habisch HJ, Royer L, et al. Genome-wide expression profiling and functional network analysis upon neuroectodermal conversion of human mesenchymal stem cells suggest HIF-1 and miR-124a as important regulators[J]. Exp Cell Res, 2010, 316(17):2760-2778.
[12]
Brambrink T, Foreman R, Welstead GG, et al. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells[J]. Cell Stem Cell, 2008, 27(2)151-159.
[13]
Stadtfeld M, Maherali N, Breault D. T, et al. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse[J]. Cell Stem Cell, 2008, 2(3)230-240.
[14]
Kim J, Efe JA, Zhu S, et al. Direct reprogramming of mouse fibroblasts to neural progenitors[J]. Proc Natl Acad Sci USA, 2011, 108(19)7838-7843.
[15]
Lujan E, Chanda S, Ahlenius H, et al. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells[J]. Proc Natl Acad Sci USA, 2012, 109(7)2527-2532.
[16]
Ring KL, Tong LM, Balestra ME, et al. Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor[J]. Cell Stem Cell, 2012, 11(1)100-109.
[17]
Yu J, Hu K, Smuga-Otto K, et al. Human induced pluripotent stem cells free of vector and transgene sequences[J]. Science, 2009, 324(5928):797-801.
[18]
Okita K, Nakagawa M, Hyenjong H, et al. Generation of mouse induced pluripotent stem cells without viral vectors[J]. Science, 2008, 322(5903):949-953.
[19]
Kim D, Kim CH, Moon JI, et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins[J]. Cell Stem Cell, 2009, 4(6):472-476.
[20]
Chen S, Zhang Q, Wu X, et al. Dedifferentiation of lineage-committed cells by a small molecule[J]. J Am Chem Soc, 2004, 126(2):410-411.
[21]
Bain G, Kitchens D, Yao M, et al. Embryonic stem cells express neuronal properties in vitro[J]. Dev Biol, 1995, 168:342-357.
[22]
Lee SH, Lumelsky N, Studer L, et al. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells[J]. Nat Biotechnol, 2000, 18(6):675-679.
[23]
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors[J]. Cell, 2006, 126(4):663-676.
[24]
Park IH, Arora N, Huo H, et al. Disease-specific induced pluripotent stem cells[J]. Cell, 2008, 134(5):877-886.
[25]
Marchetto MC, Carromeu C, Acab A, et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells[J]. Cell, 2010, 143(4):527-539.
[26]
Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons[J]. Science, 2008, 321(5893):1218-1221.
[27]
Hermann A, Storch A. Induced neural stem cells(iNSCs)in neurodegenerative diseases[J]. J Neural Transm, 2013, 120(Suppl 1):S19-S25.
[28]
Ambasudhan R, Talantova M, Coleman R, et al. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions[J]. Cell Stem Cell, 2011, 9:113-118.
[29]
Pfisterer U, Kirkeby A, Torper O, et al. Direct conversion of human fibroblasts to dopaminergic neurons[J]. Proc Natl Acad Sci USA, 2011, 108:10343-10348.
[30]
Yoo AS, Sun AX, Li L, et al. MicroRNA-mediated conversion of human fibroblasts to neurons[J]. Nature, 2011, 476:228-231.
[31]
Xue Y, Ouyang K, Huang J, et al. Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits[J]. Cell, 2013, 152(1-2):82-96.
[32]
Hanna J, Saha K, Pando B, et al. Direct cell reprogramming is a stochastic process amenable to acceleration[J]. Nature, 2009, 462(7273)595-601.
[33]
Stadtfeld M, Nagaya M, Utikal J, et al. Induced pluripotent stem cells generated without viral integration[J]. Science, 2008b, 322(5903)945-949.
[34]
Thier M, W?rsd?rfer P, Lakes YB, et al. Direct conversion of fibroblasts into stably expandable neural stem cells[J]. Cell Stem Cell, 2012, 10(4)473-479.
[35]
Han DW, Tapia N, Hermann A, et al. Direct reprogramming of fibroblasts into neural stem cells by defined factors[J]. Cell Stem Cell, 2012, 10(4)465-472.
[36]
Stadtfeld M, Nagaya M, Utikal J, et al. Induced pluripotent stem cells generated without viral integration[J]. Science, 2008, 322(5903):945-949.
[37]
Kaji K, Norrby K, Paca A, et al. Virus-free induction of pluripotency and subsequent excision of reprogramming factors[J]. Nature, 2009, 458(7239):771-775.
Zhou H, Wu S, Joo JY, et al. Generation of induced pluripotent stem cells using recombinant proteins[J]. Cell Stem Cell, 2009, 4(5):381-384.
[40]
Warren L, Manos PD, Ahfeldt T, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA[J]. Cell Stem Cell, 2010, 7(5):618-630.
[41]
Huangfu D, Maehr R, Guo W, et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds[J]. Nat Biotechnol, 2008, 26(7):795-797.
[42]
Anokye-Danso F, Trivedi CM, Juhr D, et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency[J]. Cell Stem Cell, 2011, 8(4):376-388.